RF Safe

In-vivo measurement of radio frequency electric fields in mice brain

Biosensors & bioelectronics: X · 2023 · Unclear · Insufficient evidence

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UnclearInsufficient evidencePaper 330

The study introduces a technique for direct in-vivo measurement of RF electric fields in living tissue. Proof-of-principle measurements were performed in rodent brains using BSO crystals under varying RF energy levels, with calibration/verification using in-v…

Study snapshot

PublicationBiosensors & bioelectronics: X · 2023
Study typeexposure_assessment
Reported directionUnclear
Evidence ratingInsufficient

Abstract

In-vivo measurement of radio frequency electric fields in mice brain Yaghmazadeh O, Schoenhardt S, Sarabandi A, Sabet A, Sabet K, Safari F, Alon L, Buzsáki G. In-vivo measurement of radio frequency electric fields in mice brain. Biosens Bioelectron X. 2023 Sep;14:100328. doi: 10.1016/j.biosx.2023.100328. Abstract With the development of novel technologies, radio frequency (RF) energy exposure is expanding at various wavelengths and power levels. These developments necessitate updated approaches of RF measurements in complex environments, particularly in live biological tissue. Accurate dosimetry of the absorbed RF electric fields (E-Fields) by the live tissue is the keystone of environmental health considerations for this type of ever-growing non-ionizing radiation energy. In this study, we introduce a technique for direct in-vivo measurement of electric fields in living tissue. Proof of principle in-vivo electric field measurements were conducted in rodent brains using Bismuth Silicon Oxide (BSO) crystals exposed to varying levels of RF energy. Electric field measurements were calibrated and verified using in-vivo temperature measurements using optical temperature fibers alongside electromagnetic field simulations of a transverse electromagnetic (TEM) cell. pubmed.ncbi.nlm.nih.gov

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeexposure_assessment
Effect directionunclear
PopulationRodents (mice/rodent brains; in-vivo measurements)
Sample sizeNot supplied
ExposureRF
Evidence strengthInsufficientConfidence: 74% · Peer reviewed: yes

Main findings

The study introduces a technique for direct in-vivo measurement of RF electric fields in living tissue. Proof-of-principle measurements were performed in rodent brains using BSO crystals under varying RF energy levels, with calibration/verification using in-vivo temperature measurements and TEM-cell electromagnetic simulations.

Outcomes measured

  • In-vivo RF electric field (E-field) measurements in brain tissue
  • Calibration/verification via in-vivo temperature measurements (optical temperature fibers)
  • Electromagnetic field simulations of a TEM cell for verification

Limitations

  • Frequency, power levels, and exposure duration are not specified in the abstract
  • No sample size or detailed experimental design parameters reported in the abstract
  • Focus is on measurement/dosimetry method rather than health outcomes
View raw extracted JSON
{
  "study_type": "exposure_assessment",
  "exposure": {
    "band": "RF",
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Rodents (mice/rodent brains; in-vivo measurements)",
  "sample_size": null,
  "outcomes": [
    "In-vivo RF electric field (E-field) measurements in brain tissue",
    "Calibration/verification via in-vivo temperature measurements (optical temperature fibers)",
    "Electromagnetic field simulations of a TEM cell for verification"
  ],
  "main_findings": "The study introduces a technique for direct in-vivo measurement of RF electric fields in living tissue. Proof-of-principle measurements were performed in rodent brains using BSO crystals under varying RF energy levels, with calibration/verification using in-vivo temperature measurements and TEM-cell electromagnetic simulations.",
  "effect_direction": "unclear",
  "limitations": [
    "Frequency, power levels, and exposure duration are not specified in the abstract",
    "No sample size or detailed experimental design parameters reported in the abstract",
    "Focus is on measurement/dosimetry method rather than health outcomes"
  ],
  "evidence_strength": "insufficient",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "radiofrequency",
    "RF",
    "electric field",
    "E-field",
    "in-vivo measurement",
    "dosimetry",
    "rodent brain",
    "mice",
    "Bismuth Silicon Oxide",
    "BSO crystal",
    "temperature measurement",
    "optical temperature fiber",
    "TEM cell",
    "electromagnetic simulation"
  ],
  "suggested_hubs": [
    {
      "slug": "exposure-assessment-dosimetry",
      "weight": 0.9,
      "reason": "Primary aim is development and validation of an in-vivo RF E-field measurement/dosimetry technique in brain tissue."
    }
  ]
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1016/j.biosx.2023.100328
PubMed: 37649960

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