Behavioral in-effectiveness of high frequency electromagnetic field in mice.

Physiology & behavior · 2015 · No effect · Low evidence

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No effectLow evidencePaper 4645

Mice exposed to 2.45 GHz HF-EMF for 60 min/day for up to 120 days showed no anxiety-like, OCD-like, or depression-like behavioral changes on the reported tests.

Study snapshot

PublicationPhysiology & behavior · 2015

Study typeanimal

Reported directionNo effect

Evidence ratingLow

Abstract

The present investigation was carried out with an objective to study the influence of high frequency electromagnetic field (HF-EMF) on anxiety, obsessive compulsive disorder (OCD) and depression-like behavior. For exposure to HF-EMF, non-magnetic material was used to fabricate the housing. Mice were exposed to HF-EMF (2.45GHz), 60min/day for 7 or 30 or 60 or 90 or 120days. The exposure was carried out by switching-on inbuilt class-I BLUETOOTH device that operates on 2.45GHz frequency in file transfer mode at a peak density of 100mW. Mice were subjected to the assessment of anxiety, OCD and depression-like behavior for 7 or 30 or 60 or 90 or 120days of exposure. The anxiety-like behavior was assessed by elevated plus maze, open field test and social interaction test. OCD-like behavior was assessed by marble burying behavior, whereas depression-like behavior was assessed by forced swim test and tail suspension test. The present experiment demonstrates that up to 120days of exposure to HF-EMF does not produce anxiety, OCD and depression-like behavior in mice.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal

Effect directionno_effect

PopulationMice

Sample sizeNot supplied

ExposureRF · 2450 MHz · 60 min/day for 7, 30, 60, 90, or 120 days

Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

Mice exposed to 2.45 GHz HF-EMF for 60 min/day for up to 120 days showed no anxiety-like, OCD-like, or depression-like behavioral changes on the reported tests.

Outcomes measured

Anxiety-like behavior (elevated plus maze, open field test, social interaction test)
OCD-like behavior (marble burying)
Depression-like behavior (forced swim test, tail suspension test)

Limitations

Sample size not reported in abstract
No SAR or dosimetry details reported beyond peak density/peak power (100 mW)
Exposure characterization limited to a Bluetooth device in file transfer mode

View raw extracted JSON

{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": "bluetooth device",
    "frequency_mhz": 2450,
    "sar_wkg": null,
    "duration": "60 min/day for 7, 30, 60, 90, or 120 days"
  },
  "population": "Mice",
  "sample_size": null,
  "outcomes": [
    "Anxiety-like behavior (elevated plus maze, open field test, social interaction test)",
    "OCD-like behavior (marble burying)",
    "Depression-like behavior (forced swim test, tail suspension test)"
  ],
  "main_findings": "Mice exposed to 2.45 GHz HF-EMF for 60 min/day for up to 120 days showed no anxiety-like, OCD-like, or depression-like behavioral changes on the reported tests.",
  "effect_direction": "no_effect",
  "limitations": [
    "Sample size not reported in abstract",
    "No SAR or dosimetry details reported beyond peak density/peak power (100 mW)",
    "Exposure characterization limited to a Bluetooth device in file transfer mode"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "high frequency electromagnetic field",
    "HF-EMF",
    "RF",
    "2.45 GHz",
    "Bluetooth",
    "mice",
    "anxiety",
    "OCD",
    "depression-like behavior",
    "behavioral tests"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1016/j.physbeh.2014.12.019
PubMed: 25496977

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