[Evaluation of bone density in rats after hydrocortisone and microwave radiation].

Chirurgia narzadow ruchu i ortopedia polska · 1997 · Benefit · Very low evidence

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BenefitVery low evidencePaper 6341

In rats receiving intraperitoneal hydrocortisone hemisuccinate for 12 weeks, concomitant microwave irradiation at two power densities was reported to have a protective effect on bone tissue exposed to corticotherapy.

Study snapshot

PublicationChirurgia narzadow ruchu i ortopedia polska · 1997
Study typeanimal
Reported directionBenefit
Evidence ratingVery low

Abstract

The influence of hydrocortisone and microwave radiation on bone in rats have been investigated. Hydrocortisone hemisuccinate has been administered intraperitoneally for 12 weeks with concomitant microwave irradiation of two power densities. The results achieved indicate protective effect of electromagnetic microwave radiation on bone tissue exposed to corticotherapy.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionbenefit
Populationrats
Sample sizeNot supplied
Exposuremicrowave · 12 weeks (concomitant with hydrocortisone)
Evidence strengthVery lowConfidence: 62% · Peer reviewed: yes

Main findings

In rats receiving intraperitoneal hydrocortisone hemisuccinate for 12 weeks, concomitant microwave irradiation at two power densities was reported to have a protective effect on bone tissue exposed to corticotherapy.

Outcomes measured

  • bone density
  • bone tissue effects during corticotherapy

Limitations

  • No sample size reported in abstract.
  • Microwave frequency and SAR not reported in abstract.
  • Power density values not reported in abstract.
  • Outcome measurement methods for bone density not described in abstract.
  • No details on randomization/blinding or control groups in abstract.
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": "12 weeks (concomitant with hydrocortisone)"
  },
  "population": "rats",
  "sample_size": null,
  "outcomes": [
    "bone density",
    "bone tissue effects during corticotherapy"
  ],
  "main_findings": "In rats receiving intraperitoneal hydrocortisone hemisuccinate for 12 weeks, concomitant microwave irradiation at two power densities was reported to have a protective effect on bone tissue exposed to corticotherapy.",
  "effect_direction": "benefit",
  "limitations": [
    "No sample size reported in abstract.",
    "Microwave frequency and SAR not reported in abstract.",
    "Power density values not reported in abstract.",
    "Outcome measurement methods for bone density not described in abstract.",
    "No details on randomization/blinding or control groups in abstract."
  ],
  "evidence_strength": "very_low",
  "confidence": 0.62,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "microwave radiation",
    "electromagnetic radiation",
    "hydrocortisone",
    "corticotherapy",
    "bone density",
    "rats"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: Not supplied
PubMed: 9273257

Read the original paper →

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