Alteration of life span of mice chronically exposed to 2.45 GHz CW microwaves.

Bioelectromagnetics · 1994 · Mixed · Low evidence

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MixedLow evidencePaper 6309

Mice exposed chronically to 2.45 GHz CW microwaves at 10 mW/cm2 (SAR 6.8 W/kg) had a significantly shorter average life span than sham-exposed controls (572 vs 706 days; P=.049; truncation >20%). Mice exposed at 3 mW/cm2 (SAR 2.0 W/kg) had a slightly but not …

Study snapshot

PublicationBioelectromagnetics · 1994

Study typeanimal

Reported directionMixed

Evidence ratingLow

Abstract

Female CD1 mice were exposed from the thirty-fifth day of age for the remainder of their lives to 2.45 GHz, CW-microwave radiation at a power density of 3 or 10 mW/cm2 (SAR = 2.0 or 6.8 W/kg). Exposures took place 1 h/day, 5 day/week in an anechoic chamber at an ambient temperature of 22 degrees C and a relative humidity of 50%. There were 25 animals in each exposure group, and an equal number of controls were concurrently sham exposed. The average life span of animals exposed at 10 mW/cm2 was significantly shorter than that of sham-exposed controls (572 days vs. 706 days; P = .049; truncation > 20%). In contrast, the average lifespan of the animals exposed at 3 mW/cm2 was slightly, but not significantly, longer (738 days) than that of controls (706 days).

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal

Effect directionmixed

PopulationFemale CD1 mice

Sample size75

Exposuremicrowave · 2450 MHz · 1 h/day, 5 day/week; from 35th day of age for remainder of life

Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Outcomes measured

life span
mortality/longevity

Limitations

Only female CD1 mice were studied.
Exposure was limited to 1 h/day, 5 days/week (not continuous).
Only two exposure levels were tested; one showed decreased lifespan while the lower level did not show a significant effect.

View raw extracted JSON

{
  "study_type": "animal",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": 2450,
    "sar_wkg": null,
    "duration": "1 h/day, 5 day/week; from 35th day of age for remainder of life"
  },
  "population": "Female CD1 mice",
  "sample_size": 75,
  "outcomes": [
    "life span",
    "mortality/longevity"
  ],
  "main_findings": "Mice exposed chronically to 2.45 GHz CW microwaves at 10 mW/cm2 (SAR 6.8 W/kg) had a significantly shorter average life span than sham-exposed controls (572 vs 706 days; P=.049; truncation >20%). Mice exposed at 3 mW/cm2 (SAR 2.0 W/kg) had a slightly but not significantly longer average life span than controls (738 vs 706 days).",
  "effect_direction": "mixed",
  "limitations": [
    "Only female CD1 mice were studied.",
    "Exposure was limited to 1 h/day, 5 days/week (not continuous).",
    "Only two exposure levels were tested; one showed decreased lifespan while the lower level did not show a significant effect."
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "2.45 GHz",
    "microwave",
    "CW",
    "chronic exposure",
    "mouse",
    "CD1",
    "life span",
    "SAR",
    "power density",
    "anechoic chamber",
    "sham exposure"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1002/bem.2250150302
PubMed: 8074734

Read the original paper →

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