No clastogenic effect from in vitro microwave irradiation of G0 human lymphocytes.

International journal of radiation biology and related studies in physics, chemistry, and medicine · 1984 · No effect · Low evidence

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No effectLow evidencePaper 5915

Human blood specimens exposed to 2.45 GHz microwave radiation at specific energy absorption rates of 104 or 193 W/kg (below 36°C) showed chromosome damage that did not exceed control levels, including unstable chromosome/chromatid aberrations and sister chrom…

Study snapshot

PublicationInternational journal of radiation biology and related studies in physics, chemistry, and medicine · 1984
Study typein_vitro
Reported directionNo effect
Evidence ratingLow

Abstract

Specimens of human blood were exposed at specific energy absorption rates of 104 or 193 W kg-1 to 2.45 GHz microwave radiation at temperatures below 36 degrees C. Cultured lymphocytes were examined for induced unstable chromosome and chromatid aberrations and sister chromatid exchanges. The amount of chromosome damage observed did not exceed that found in controls.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typein_vitro
Effect directionno_effect
PopulationG0 human lymphocytes (from human blood specimens)
Sample sizeNot supplied
Exposuremicrowave · 2450 MHz
Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Human blood specimens exposed to 2.45 GHz microwave radiation at specific energy absorption rates of 104 or 193 W/kg (below 36°C) showed chromosome damage that did not exceed control levels, including unstable chromosome/chromatid aberrations and sister chromatid exchanges.

Outcomes measured

  • unstable chromosome aberrations
  • chromatid aberrations
  • sister chromatid exchanges

Limitations

  • Sample size not reported in abstract.
  • Exposure duration not reported in abstract.
  • Only in vitro endpoints assessed; generalizability to in vivo outcomes not addressed in abstract.
View raw extracted JSON
{
  "study_type": "in_vitro",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": 2450,
    "sar_wkg": null,
    "duration": null
  },
  "population": "G0 human lymphocytes (from human blood specimens)",
  "sample_size": null,
  "outcomes": [
    "unstable chromosome aberrations",
    "chromatid aberrations",
    "sister chromatid exchanges"
  ],
  "main_findings": "Human blood specimens exposed to 2.45 GHz microwave radiation at specific energy absorption rates of 104 or 193 W/kg (below 36°C) showed chromosome damage that did not exceed control levels, including unstable chromosome/chromatid aberrations and sister chromatid exchanges.",
  "effect_direction": "no_effect",
  "limitations": [
    "Sample size not reported in abstract.",
    "Exposure duration not reported in abstract.",
    "Only in vitro endpoints assessed; generalizability to in vivo outcomes not addressed in abstract."
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "in vitro",
    "microwave",
    "2.45 GHz",
    "specific energy absorption rate",
    "SAR",
    "human lymphocytes",
    "chromosome aberrations",
    "chromatid aberrations",
    "sister chromatid exchanges",
    "clastogenic"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1080/09553008414551211
PubMed: 6332088

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