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Dosimetry for a study of effects of 2.45-GHz microwaves on mouse testis.

Bioelectromagnetics · 1980 · Unclear · Low evidence

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UnclearLow evidencePaper 6034

The study measured power density at cage positions and performed absorption measurements in mouse carcasses, including whole-body SAR, energy-deposition patterns, and local SAR in testis. It concluded that SAR in the testis was considerably less than whole-bo…

Study snapshot

PublicationBioelectromagnetics · 1980
Study typeanimal
Reported directionUnclear
Evidence ratingLow

Abstract

In order to determine the effects of microwave radiation on the testis, it is necessary to express the physical insult in animal studies in a way that can be replicated elsewhere and ultimately used as a basis for extrapolation to man. However, there is conflict--especially in chronic experiments--between the desire for precise dosimetry and the need to minimise alteration of the normal physiological functions of the animals. The compromise arrangement used in this study was to house the mice singly, in cages with limited food and water, and to irradiate them for up to 30 days (16 h/day) in an anechoic chamber. The only measurements taken routinely were of power density in the positions normally occupied by the cages. In addition, a series of absorption measurements was made in mouse carcasses: Whole-body specific absorption rate (SAR); energy-deposition patterns (determined thermographically); and local SAR in testis (using a miniature electric (E)-field probe). It was concluded that the SAR in testis was considerably less than the whole-body SAR. Exposure for 16 h at 50 mW/cm2 elevated rectal but not testis temperature, thus demonstrating the ability of the conscious mouse to regulate the temperature of its testis.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionunclear
Populationmice
Sample sizeNot supplied
Exposuremicrowave · 2450 MHz · up to 30 days (16 h/day); also notes exposure for 16 h at 50 mW/cm2
Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

The study measured power density at cage positions and performed absorption measurements in mouse carcasses, including whole-body SAR, energy-deposition patterns, and local SAR in testis. It concluded that SAR in the testis was considerably less than whole-body SAR. Exposure for 16 h at 50 mW/cm2 elevated rectal temperature but not testis temperature.

Outcomes measured

  • dosimetry (power density, whole-body SAR, local SAR in testis, energy-deposition patterns)
  • rectal temperature
  • testis temperature

Limitations

  • No sample size reported in abstract
  • Routine measurements were limited to power density at cage positions
  • Absorption/SAR measurements were made in mouse carcasses (not in vivo)
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": 2450,
    "sar_wkg": null,
    "duration": "up to 30 days (16 h/day); also notes exposure for 16 h at 50 mW/cm2"
  },
  "population": "mice",
  "sample_size": null,
  "outcomes": [
    "dosimetry (power density, whole-body SAR, local SAR in testis, energy-deposition patterns)",
    "rectal temperature",
    "testis temperature"
  ],
  "main_findings": "The study measured power density at cage positions and performed absorption measurements in mouse carcasses, including whole-body SAR, energy-deposition patterns, and local SAR in testis. It concluded that SAR in the testis was considerably less than whole-body SAR. Exposure for 16 h at 50 mW/cm2 elevated rectal temperature but not testis temperature.",
  "effect_direction": "unclear",
  "limitations": [
    "No sample size reported in abstract",
    "Routine measurements were limited to power density at cage positions",
    "Absorption/SAR measurements were made in mouse carcasses (not in vivo)"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "2.45 GHz",
    "microwaves",
    "mouse",
    "testis",
    "dosimetry",
    "power density",
    "specific absorption rate",
    "SAR",
    "temperature",
    "anechoic chamber"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1002/bem.2250010308
PubMed: 7284029

Read the original paper →

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