Ultrastructural changes in the rabbit lens induced by microwave radiation.

Annals of the New York Academy of Sciences · 1975 · Harm · Very low evidence

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HarmVery low evidencePaper 6141

Rabbits were exposed to 2450-MHz continuous microwave radiation and lens effects were assessed by slit-lamp examination. Electron microscopy of two selected lenses (one severely damaged by slit-lamp exam and one appearing unaffected) found prominent ultrastru…

Study snapshot

PublicationAnnals of the New York Academy of Sciences · 1975
Study typeanimal
Reported directionHarm
Evidence ratingVery low

Abstract

Rabbits were irradiated with 2450-MHz continuous microwave energy. Effects of the radiation on the ocular lens were assessed by slit-lamp biomicroscopic examination of the eye. Two lenses were selected for electron microscopy, one that was severely damaged and one that appeared unaffected by the radiation. There were prominent ultrastructural changes in both lenses.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionharm
PopulationRabbits
Sample sizeNot supplied
Exposuremicrowave · 2450 MHz
Evidence strengthVery lowConfidence: 66% · Peer reviewed: yes

Main findings

Rabbits were exposed to 2450-MHz continuous microwave radiation and lens effects were assessed by slit-lamp examination. Electron microscopy of two selected lenses (one severely damaged by slit-lamp exam and one appearing unaffected) found prominent ultrastructural changes in both lenses.

Outcomes measured

  • Ocular lens damage
  • Ultrastructural (electron microscopy) changes in the lens

Limitations

  • Sample size not reported in abstract
  • Only two lenses were selected for electron microscopy
  • Exposure metrics beyond frequency (e.g., power density/SAR, duration) not reported in abstract
  • Selection of lenses for electron microscopy may introduce selection bias
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": 2450,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Rabbits",
  "sample_size": null,
  "outcomes": [
    "Ocular lens damage",
    "Ultrastructural (electron microscopy) changes in the lens"
  ],
  "main_findings": "Rabbits were exposed to 2450-MHz continuous microwave radiation and lens effects were assessed by slit-lamp examination. Electron microscopy of two selected lenses (one severely damaged by slit-lamp exam and one appearing unaffected) found prominent ultrastructural changes in both lenses.",
  "effect_direction": "harm",
  "limitations": [
    "Sample size not reported in abstract",
    "Only two lenses were selected for electron microscopy",
    "Exposure metrics beyond frequency (e.g., power density/SAR, duration) not reported in abstract",
    "Selection of lenses for electron microscopy may introduce selection bias"
  ],
  "evidence_strength": "very_low",
  "confidence": 0.66,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "rabbit",
    "microwave radiation",
    "2450 MHz",
    "ocular lens",
    "slit-lamp biomicroscopy",
    "electron microscopy",
    "ultrastructural changes"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1111/j.1749-6632.1975.tb35993.x
PubMed: 1054229

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