[Effect of microwave radiation on regional blood flow and tissue oxygenation in the brain].

{
  "study_type": "animal",
  "exposure": {
    "band": "microwave",
    "source": "localized CNS irradiation",
    "frequency_mhz": 2450,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Rabbits",
  "sample_size": null,
  "outcomes": [
    "regional cerebral blood flow",
    "tissue oxygenation/oxygen tension",
    "cerebral circulation regulation",
    "hyperemia",
    "hyperoxia",
    "hyperthermia"
  ],
  "main_findings": "In rabbits, local irradiation of exposed cerebral cortex with 2450 MHz microwaves (5–40 W) produced hyperemia and hyperoxia in the exposed zone, attributed to a hyperthermal effect. Irradiation of the medulla oblongata at low power not leading to hyperthermia increased circulation and oxygen tension across the whole brain, reportedly due to impaired regulation of cerebral blood flow and oxygen supply.",
  "effect_direction": "mixed",
  "limitations": [
    "Sample size not reported in the abstract",
    "Exposure duration not reported",
    "Dosimetry (e.g., SAR) not reported",
    "Details of experimental design and controls not provided in the abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "microwave radiation",
    "2450 MHz",
    "rabbit",
    "brain",
    "cerebral blood flow",
    "oxygen tension",
    "hyperemia",
    "hyperoxia",
    "medulla oblongata",
    "hyperthermia"
  ],
  "suggested_hubs": [
    {
      "slug": "who-icnirp",
      "weight": 0.2,
      "reason": "Microwave exposure with physiological effects; potentially relevant to exposure guideline discussions, though no policy content is provided."
    }
  ]
}