Microwave radiation and chlordiazepoxide: synergistic effects on fixed-interval behavior.

Science (New York, N.Y.) · 1979 · Mixed · Insufficient evidence

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MixedInsufficient evidencePaper 6064

In rats, low-intensity pulsed microwave radiation (average power density 1 mW/cm^2) potentiated the response-rate-increasing effects of chlordiazepoxide. The abstract states the microwave exposure alone had no apparent behavioral effects, but it modified the …

Study snapshot

PublicationScience (New York, N.Y.) · 1979
Study typeanimal
Reported directionMixed
Evidence ratingInsufficient

Abstract

In the presence of low-intensity pulsed microwave radiation, at an average power density of 1 milliwatt per square centimeter, the response-rate-increasing effects of chlordiazepoxide were potentiated in rats. The behavioral effects of a drug can be modified by brief exposure to a low-level microwave field even when the radiation level alone has no apparent effects on the behavior.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionmixed
PopulationRats
Sample sizeNot supplied
Exposuremicrowave · brief exposure
Evidence strengthInsufficientConfidence: 74% · Peer reviewed: yes

Main findings

In rats, low-intensity pulsed microwave radiation (average power density 1 mW/cm^2) potentiated the response-rate-increasing effects of chlordiazepoxide. The abstract states the microwave exposure alone had no apparent behavioral effects, but it modified the drug’s behavioral effects.

Outcomes measured

  • Fixed-interval behavior
  • Response rate (behavioral)
  • Drug-behavior interaction (chlordiazepoxide potentiation)

Limitations

  • Sample size not reported in abstract
  • Microwave frequency not reported in abstract
  • Exposure duration not quantified beyond 'brief'
  • Outcome details and statistical results not provided in abstract
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": "brief exposure"
  },
  "population": "Rats",
  "sample_size": null,
  "outcomes": [
    "Fixed-interval behavior",
    "Response rate (behavioral)",
    "Drug-behavior interaction (chlordiazepoxide potentiation)"
  ],
  "main_findings": "In rats, low-intensity pulsed microwave radiation (average power density 1 mW/cm^2) potentiated the response-rate-increasing effects of chlordiazepoxide. The abstract states the microwave exposure alone had no apparent behavioral effects, but it modified the drug’s behavioral effects.",
  "effect_direction": "mixed",
  "limitations": [
    "Sample size not reported in abstract",
    "Microwave frequency not reported in abstract",
    "Exposure duration not quantified beyond 'brief'",
    "Outcome details and statistical results not provided in abstract"
  ],
  "evidence_strength": "insufficient",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "pulsed microwave radiation",
    "low-intensity",
    "power density",
    "1 mW/cm^2",
    "chlordiazepoxide",
    "synergistic effects",
    "fixed-interval behavior",
    "rats",
    "behavior"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1126/science.424759
PubMed: 424759

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