[Reaction of the brain receptor system to the effect of low intensity microwaves].

Biofizika · 1996 · Mixed · Low evidence

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MixedLow evidencePaper 6326

Low-intensity microwave exposure was reported to alter agonist binding to brain glutamate and GABA receptors when power density exceeded 50 microW/cm2. Effects were described as dependent on low-frequency modulation, with statistically significant changes in …

Study snapshot

PublicationBiofizika · 1996

Study typeanimal

Reported directionMixed

Evidence ratingLow

Abstract

We have found that two important brain synaptic receptor systems are very sensitive to the influence of low intensity microwaves. Both the excitatory glutamatergic and the inhibitory GABAergic are affected by microwave exposure. Power densities higher 50 microW/cm2 caused changes in the binding properties of these receptors to agonists. Low frequence modulation of microwaves was essential for these effects. Statistically significant effects on mean value of binding were observed at 16 Hz modulation. Exposure to microwave radiation changes the binding of agonists to glutamate and GABA receptors in different ways. An increase was observed for glutamate and a decrease for GABA. We suppose that the effect of microwaves is related to the stress reactions of the organism.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal

Effect directionmixed

PopulationNot supplied

Sample sizeNot supplied

Exposuremicrowave

Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

Outcomes measured

Glutamate (glutamatergic) receptor agonist binding properties
GABA (GABAergic) receptor agonist binding properties

Limitations

No species/animal model described in the abstract
Sample size not reported
Microwave carrier frequency not reported
Exposure duration not reported
SAR not reported
Methods and brain regions/receptor subtypes not specified

View raw extracted JSON

{
  "study_type": "animal",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": null,
  "sample_size": null,
  "outcomes": [
    "Glutamate (glutamatergic) receptor agonist binding properties",
    "GABA (GABAergic) receptor agonist binding properties"
  ],
  "main_findings": "Low-intensity microwave exposure was reported to alter agonist binding to brain glutamate and GABA receptors when power density exceeded 50 microW/cm2. Effects were described as dependent on low-frequency modulation, with statistically significant changes in mean binding observed at 16 Hz modulation; glutamate binding increased while GABA binding decreased.",
  "effect_direction": "mixed",
  "limitations": [
    "No species/animal model described in the abstract",
    "Sample size not reported",
    "Microwave carrier frequency not reported",
    "Exposure duration not reported",
    "SAR not reported",
    "Methods and brain regions/receptor subtypes not specified"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "microwaves",
    "low-intensity",
    "power density",
    "50 microW/cm2",
    "low-frequency modulation",
    "16 Hz",
    "glutamate receptor",
    "GABA receptor",
    "agonist binding",
    "brain synaptic receptors"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: Not supplied
PubMed: 8962884

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