In vitro study of microwave effects on calcium efflux in rat brain tissue.

Bioelectromagnetics · 1981 · No effect · Low evidence

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No effectLow evidencePaper 6000

Rat cerebral tissue exposed in vitro to pulsed microwave radiation (1 GHz) at low pulse repetition frequencies (16 or 32 Hz) and average power densities ranging from 0.5 to 15 mW/cm2 showed no alteration in 45Ca2+ efflux compared with controls.

Study snapshot

PublicationBioelectromagnetics · 1981

Study typein_vitro

Reported directionNo effect

Evidence ratingLow

Abstract

In this study we investigated the prospect of microwave-induced alteration of 45Ca2+ efflux from rat neural tissue at low pulse repetition frequencies and low power densities under in vitro conditions. Rat cerebral tissue, preloaded with 45Ca2+, was exposed to pulsed-microwave radiation (1-GHz carrier frequency) according to one of several PRF-power density exposure schemes: 16 Hz at 0.5, 1.0, 2.0, or 15 mW/cm2, or 32 Hz at 1.0 or 2.0 mW/cm2 average power density. Measurements of radioactivity in the efflux medium and in the tissue sample were used to calculate an efflux value for each sample. The results indicate that the radiation conditions used did not alter calcium efflux in rat brain tissue.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typein_vitro

Effect directionno_effect

PopulationRat cerebral (brain) tissue (in vitro), preloaded with 45Ca2+

Sample sizeNot supplied

Exposuremicrowave · 1000 MHz

Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Outcomes measured

45Ca2+ (calcium) efflux from rat neural tissue

Limitations

Sample size not reported in abstract.
Exposure duration not reported in abstract.
Specific control/sham conditions and statistical methods not described in abstract.
Only calcium efflux outcome assessed; generalizability to other endpoints is unclear from abstract.

View raw extracted JSON

{
  "study_type": "in_vitro",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": 1000,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Rat cerebral (brain) tissue (in vitro), preloaded with 45Ca2+",
  "sample_size": null,
  "outcomes": [
    "45Ca2+ (calcium) efflux from rat neural tissue"
  ],
  "main_findings": "Rat cerebral tissue exposed in vitro to pulsed microwave radiation (1 GHz) at low pulse repetition frequencies (16 or 32 Hz) and average power densities ranging from 0.5 to 15 mW/cm2 showed no alteration in 45Ca2+ efflux compared with controls.",
  "effect_direction": "no_effect",
  "limitations": [
    "Sample size not reported in abstract.",
    "Exposure duration not reported in abstract.",
    "Specific control/sham conditions and statistical methods not described in abstract.",
    "Only calcium efflux outcome assessed; generalizability to other endpoints is unclear from abstract."
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "in vitro",
    "microwave",
    "pulsed microwave",
    "1 GHz",
    "pulse repetition frequency",
    "power density",
    "rat brain tissue",
    "cerebral tissue",
    "calcium efflux",
    "45Ca2+"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1002/bem.2250020207
PubMed: 7295363

Read the original paper →

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