Measurement of ventilatory frequency in unrestrained rodents using microwave radiation.

Respiration physiology · 1984 · Unclear · Insufficient evidence

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UnclearInsufficient evidencePaper 5919

A remote method to determine breathing frequency in unrestrained mice was described using a rectangular waveguide at 2450 MHz. Rhythmic changes in microwave power transmitted through the waveguide tracked inspiration/expiration due to changes in the mouse’s a…

Study snapshot

PublicationRespiration physiology · 1984

Study typeengineering

Reported directionUnclear

Evidence ratingInsufficient

Abstract

A novel technique for remote determination of breathing frequency in unrestrained rodents using microwave radiation is described. Single mice were placed inside a rectangular waveguide operating at 2450 MHz. Because mice efficiently absorb radio frequency energy at 2450 MHz, any change in their absorption, as occurs rhythmically with breathing, can be detected by monitoring the changes in power transmitted through the waveguide. When the volume of the mouse increases during inspiration, transmitted power through the waveguide momentarily decreases - during expiration the reverse takes place. By differential amplification of the analog output of the power meter used to monitor transmitted power, breathing frequency can be easily recorded on conventional recording equipment. The microwave technique has a definite advantage over other methods in that breathing frequency can be remotely monitored without the need to attach wire leads or surgically implant telemetry probes. This greatly reduces unnecessary stress to the animal. By use of larger waveguides the principle of this technique may be applied to larger species.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeengineering

Effect directionunclear

Populationunrestrained mice (single mice)

Sample sizeNot supplied

Exposuremicrowave · 2450 MHz

Evidence strengthInsufficientConfidence: 74% · Peer reviewed: yes

Main findings

Outcomes measured

ventilatory (breathing) frequency measurement/monitoring
changes in transmitted microwave power correlated with respiration

Limitations

Sample size not reported in abstract
No quantitative performance metrics (e.g., accuracy/validation vs. reference method) reported in abstract
Exposure level (e.g., SAR/power density) and duration not reported in abstract
Not designed to assess health effects; primarily a measurement technique

View raw extracted JSON

{
  "study_type": "engineering",
  "exposure": {
    "band": "microwave",
    "source": "waveguide (microwave radiation)",
    "frequency_mhz": 2450,
    "sar_wkg": null,
    "duration": null
  },
  "population": "unrestrained mice (single mice)",
  "sample_size": null,
  "outcomes": [
    "ventilatory (breathing) frequency measurement/monitoring",
    "changes in transmitted microwave power correlated with respiration"
  ],
  "main_findings": "A remote method to determine breathing frequency in unrestrained mice was described using a rectangular waveguide at 2450 MHz. Rhythmic changes in microwave power transmitted through the waveguide tracked inspiration/expiration due to changes in the mouse’s absorption, enabling breathing frequency recording without attached leads or implanted probes.",
  "effect_direction": "unclear",
  "limitations": [
    "Sample size not reported in abstract",
    "No quantitative performance metrics (e.g., accuracy/validation vs. reference method) reported in abstract",
    "Exposure level (e.g., SAR/power density) and duration not reported in abstract",
    "Not designed to assess health effects; primarily a measurement technique"
  ],
  "evidence_strength": "insufficient",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "microwave radiation",
    "2450 MHz",
    "waveguide",
    "respiration monitoring",
    "ventilatory frequency",
    "mice",
    "remote measurement"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1016/0034-5687(84)90131-2
PubMed: 6739999

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