Effect of 2450 MHz microwave radiation on hematopoiesis of pregnant mice.

Radiation research · 1984 · No effect · Low evidence

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No effectLow evidencePaper 5912

Pregnant mice exposed to 2450 MHz continuous-wave microwave radiation at an average power density of 30 mW/cm2 for 8 hr/day during gestation days 1–6 or 6–15 showed no changes in peripheral blood total or differential leukocyte counts on day 18 of pregnancy. …

Study snapshot

PublicationRadiation research · 1984
Study typeanimal
Reported directionNo effect
Evidence ratingLow

Abstract

In this study, the influence of 2450 MHz CW microwave radiation on hematopoiesis in pregnant mice was examined. Dams (mice CD-1 strain) were irradiated during Days 1-6 or 6-15 of pregnancy. The animals were irradiated for a total of 8 hr per day (two 4-hr exposures in 9 hr) at an average power density of 30 mW/cm2. Peripheral blood and bone marrow samples were obtained on Day 18 of pregnancy. The total leukocyte and differential leukocyte counts of peripheral blood samples were not affected by either exposure regimen. In addition, no effects were noted in either the erythroid or myeloid mitotic indices of bone marrow samples. Exposure of pregnant mice to microwave radiation under the conditions of these experiments had no effects on the investigated aspects of hematopoiesis.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionno_effect
PopulationPregnant CD-1 strain mice (dams)
Sample sizeNot supplied
Exposuremicrowave · 2450 MHz · 8 hr/day (two 4-hr exposures in 9 hr) during gestation days 1–6 or 6–15
Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Pregnant mice exposed to 2450 MHz continuous-wave microwave radiation at an average power density of 30 mW/cm2 for 8 hr/day during gestation days 1–6 or 6–15 showed no changes in peripheral blood total or differential leukocyte counts on day 18 of pregnancy. No effects were observed in erythroid or myeloid mitotic indices in bone marrow.

Outcomes measured

  • Peripheral blood total leukocyte count
  • Peripheral blood differential leukocyte count
  • Bone marrow erythroid mitotic index
  • Bone marrow myeloid mitotic index

Limitations

  • Sample size not reported in the abstract
  • Specific dosimetry beyond average power density (e.g., SAR) not reported in the abstract
  • Only selected hematopoiesis endpoints assessed and measured at a single time point (day 18)
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": 2450,
    "sar_wkg": null,
    "duration": "8 hr/day (two 4-hr exposures in 9 hr) during gestation days 1–6 or 6–15"
  },
  "population": "Pregnant CD-1 strain mice (dams)",
  "sample_size": null,
  "outcomes": [
    "Peripheral blood total leukocyte count",
    "Peripheral blood differential leukocyte count",
    "Bone marrow erythroid mitotic index",
    "Bone marrow myeloid mitotic index"
  ],
  "main_findings": "Pregnant mice exposed to 2450 MHz continuous-wave microwave radiation at an average power density of 30 mW/cm2 for 8 hr/day during gestation days 1–6 or 6–15 showed no changes in peripheral blood total or differential leukocyte counts on day 18 of pregnancy. No effects were observed in erythroid or myeloid mitotic indices in bone marrow.",
  "effect_direction": "no_effect",
  "limitations": [
    "Sample size not reported in the abstract",
    "Specific dosimetry beyond average power density (e.g., SAR) not reported in the abstract",
    "Only selected hematopoiesis endpoints assessed and measured at a single time point (day 18)"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "2450 MHz",
    "microwave radiation",
    "continuous wave",
    "pregnancy",
    "mice",
    "hematopoiesis",
    "bone marrow",
    "leukocyte count",
    "power density 30 mW/cm2"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: Not supplied
PubMed: 6494447

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