Effects of 50Hz Homogeneous Ferromagnetic Field on the Concentrations of Intracellular Calcium-ion of SNU Cells and Lymphma Cells In Vitro.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference · 2005 · Harm · Low evidence

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HarmLow evidencePaper 3547

SNU cells and human peripheral blood lymphocytes showed increased intracellular calcium-ion concentration after exposure to a 50 Hz homogeneous ferromagnetic field (0.097 T) across different exposure time periods.

Study snapshot

PublicationConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference · 2005

Study typein_vitro

Reported directionHarm

Evidence ratingLow

Abstract

The study was designed to observe the effects of 50 Hz homogeneous ferromagnetic field (0.097T) exposure on change of intracellular Calcium-ion concentration of human low differentiation gastric adenocarcinoma cell line - SNU and lymphocytes in vitro. SNU cells and human peripheral blood lymphocytes in vitro were exposured to 50 Hz homogeneous ferromagnetic field at different time periods. Cells were harvested after magnetic field exposure. The concentration of intracellular Calcium-ion of cells in control and different experimental groups were measured with confocal microscope. The concentration of intracellular Calcium-ion of SNU cells and human peripheral blood lymphocytes were all increased after magnetic field exposure. 50Hz homogeneous ferromagnetic field exposure could induce increases of the concentration of intracellular Calcium-ion of SNU cells and human peripheral blood lymphocytes in vitro.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typein_vitro

Effect directionharm

PopulationHuman low differentiation gastric adenocarcinoma cell line (SNU) and human peripheral blood lymphocytes (in vitro)

Sample sizeNot supplied

ExposureELF · 0.05 MHz

Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Outcomes measured

Intracellular calcium-ion concentration (measured by confocal microscope)

Limitations

In vitro study; findings may not translate to in vivo or human health outcomes
Exposure durations/time periods not specified in the abstract
Sample size and replication not reported in the abstract
Only one biological endpoint (intracellular calcium) reported

View raw extracted JSON

{
  "study_type": "in_vitro",
  "exposure": {
    "band": "ELF",
    "source": "other",
    "frequency_mhz": 0.05,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Human low differentiation gastric adenocarcinoma cell line (SNU) and human peripheral blood lymphocytes (in vitro)",
  "sample_size": null,
  "outcomes": [
    "Intracellular calcium-ion concentration (measured by confocal microscope)"
  ],
  "main_findings": "SNU cells and human peripheral blood lymphocytes showed increased intracellular calcium-ion concentration after exposure to a 50 Hz homogeneous ferromagnetic field (0.097 T) across different exposure time periods.",
  "effect_direction": "harm",
  "limitations": [
    "In vitro study; findings may not translate to in vivo or human health outcomes",
    "Exposure durations/time periods not specified in the abstract",
    "Sample size and replication not reported in the abstract",
    "Only one biological endpoint (intracellular calcium) reported"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "50 Hz",
    "ELF magnetic field",
    "ferromagnetic field",
    "0.097 T",
    "SNU cells",
    "gastric adenocarcinoma cell line",
    "peripheral blood lymphocytes",
    "intracellular calcium",
    "confocal microscope",
    "in vitro"
  ],
  "suggested_hubs": [
    {
      "slug": "elf-magnetic-fields",
      "weight": 0.9,
      "reason": "Study examines biological effects of 50 Hz magnetic field exposure."
    }
  ]
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1109/iembs.2005.1615564
PubMed: 17281334

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