Mechanisms and therapeutic effectiveness of pulsed electromagnetic field therapy in oncology

Cancer Med. · 2016 · Unclear · Insufficient evidence

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UnclearInsufficient evidencePaper 6750

The article reviews experimental (in vitro and in vivo) and limited human evidence on pulsed electromagnetic field (PEMF) therapy across multiple cancer types, discussing potential advantages and future perspectives. It notes that application in humans has be…

Study snapshot

PublicationCancer Med. · 2016

Study typereview

Reported directionUnclear

Evidence ratingInsufficient

Abstract

Cancer is one of the most common causes of death worldwide. Available treatments are associated with numerous side effects and only a low percentage of patients achieve complete remission. Therefore, there is a strong need for new therapeutic strategies. In this regard, pulsed electromagnetic field (PEMF) therapy presents several potential advantages including non‐invasiveness, safety, lack of toxicity for non‐cancerous cells, and the possibility of being combined with other available therapies. Indeed, PEMF stimulation has already been used in the context of various cancer types including skin, breast, prostate, hepatocellular, lung, ovarian, pancreatic, bladder, thyroid, and colon cancer in vitro and in vivo. At present, only limited application of PEMF in cancer has been documented in humans. In this article, we review the experimental and clinical evidence of PEMF therapy discussing future perspectives in its use in oncology.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typereview

Effect directionunclear

PopulationNot supplied

Sample sizeNot supplied

ExposureNot supplied

Evidence strengthInsufficientConfidence: 66% · Peer reviewed: yes

Main findings

Outcomes measured

therapeutic effectiveness in oncology
mechanisms of action

Limitations

No specific PEMF exposure parameters (e.g., frequency, intensity, duration) provided in the abstract
Human evidence described as limited

View raw extracted JSON

{
  "study_type": "review",
  "exposure": {
    "band": null,
    "source": "pulsed electromagnetic field (PEMF) therapy",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": null,
  "sample_size": null,
  "outcomes": [
    "therapeutic effectiveness in oncology",
    "mechanisms of action"
  ],
  "main_findings": "The article reviews experimental (in vitro and in vivo) and limited human evidence on pulsed electromagnetic field (PEMF) therapy across multiple cancer types, discussing potential advantages and future perspectives. It notes that application in humans has been limited.",
  "effect_direction": "unclear",
  "limitations": [
    "No specific PEMF exposure parameters (e.g., frequency, intensity, duration) provided in the abstract",
    "Human evidence described as limited"
  ],
  "evidence_strength": "insufficient",
  "confidence": 0.66,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "pulsed electromagnetic field",
    "PEMF",
    "oncology",
    "cancer therapy",
    "in vitro",
    "in vivo",
    "clinical evidence"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1002/cam4.861
PubMed: 27748048

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