Search for ion-cyclotron resonance in an Na(+)-transport system

Bioelectromagnetics · 1991 · No effect · Low evidence

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No effectLow evidencePaper 6698

Across AC magnetic-field frequencies from 3 to 770 Hz with simultaneous static (10–220 microT) and time-varying (1–20 microT) magnetic fields, no discernible changes in transepithelial current were observed under tested ion-cyclotron resonance conditions for …

Study snapshot

PublicationBioelectromagnetics · 1991
Study typeanimal
Reported directionNo effect
Evidence ratingLow

Abstract

Colonic tissue from the turtle (Pseudemys scripta) was exposed in a Ussing chamber to simultaneously applied static and time-varying magnetic fields. Transepithelial differences of potential were monitored as frequency of the AC field was varied continuously or in discrete steps from 3 to 770 Hz. Density of the DC field was varied from 10 to 220 microT and that of the AC field from 1 to 20 microT. Short-circuit currents through tissue were monitored for changes that might have been observed under ion-cyclotron resonance (ICR) conditions for each of several ions: H+, Li+, Na+, K+, Ca2+, and Cl-. No discernible changes of transepithelial current were observed. The negative findings are discussed in relation to positive and negative findings that have appeared in the literature.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionno_effect
PopulationColonic tissue from turtle (Pseudemys scripta) in an Ussing chamber
Sample sizeNot supplied
ExposureELF
Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

Across AC magnetic-field frequencies from 3 to 770 Hz with simultaneous static (10–220 microT) and time-varying (1–20 microT) magnetic fields, no discernible changes in transepithelial current were observed under tested ion-cyclotron resonance conditions for several ions (H+, Li+, Na+, K+, Ca2+, Cl-).

Outcomes measured

  • Transepithelial potential difference
  • Short-circuit current (transepithelial current) changes under ion-cyclotron resonance (ICR) conditions for H+, Li+, Na+, K+, Ca2+, Cl-

Limitations

  • Sample size not reported in abstract
  • Exposure duration not reported in abstract
  • Ex vivo tissue preparation (Ussing chamber) may limit generalizability beyond the experimental system
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "ELF",
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Colonic tissue from turtle (Pseudemys scripta) in an Ussing chamber",
  "sample_size": null,
  "outcomes": [
    "Transepithelial potential difference",
    "Short-circuit current (transepithelial current) changes under ion-cyclotron resonance (ICR) conditions for H+, Li+, Na+, K+, Ca2+, Cl-"
  ],
  "main_findings": "Across AC magnetic-field frequencies from 3 to 770 Hz with simultaneous static (10–220 microT) and time-varying (1–20 microT) magnetic fields, no discernible changes in transepithelial current were observed under tested ion-cyclotron resonance conditions for several ions (H+, Li+, Na+, K+, Ca2+, Cl-).",
  "effect_direction": "no_effect",
  "limitations": [
    "Sample size not reported in abstract",
    "Exposure duration not reported in abstract",
    "Ex vivo tissue preparation (Ussing chamber) may limit generalizability beyond the experimental system"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "ion-cyclotron resonance",
    "Na+ transport",
    "Ussing chamber",
    "turtle colonic tissue",
    "static magnetic field",
    "time-varying magnetic field",
    "ELF magnetic fields",
    "transepithelial potential",
    "short-circuit current"
  ],
  "suggested_hubs": [
    {
      "slug": "elf-emf",
      "weight": 0.78,
      "reason": "Study tests biological effects of extremely low frequency (3–770 Hz) magnetic fields with a static field component."
    },
    {
      "slug": "ion-cyclotron-resonance",
      "weight": 0.86,
      "reason": "Explicitly investigates ion-cyclotron resonance conditions for multiple ions."
    }
  ]
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1002/bem.2250120203
PubMed: 2039558

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