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B16 melanoma development in black mice exposed to low-level microwave radiation.

Bioelectromagnetics · 1988 · No effect · Low evidence

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No effectLow evidencePaper 6241

In black C57/6J mice with B16 melanoma, low-level 2,450 MHz microwave exposure (1 mW/cm2; SAR 1.2 mW/g) for up to 690 hours showed no significant effects on tumor development or survival compared with controls. No significant differences were observed between…

Study snapshot

PublicationBioelectromagnetics · 1988
Study typeanimal
Reported directionNo effect
Evidence ratingLow

Abstract

The effect of low-level microwave exposure, 2,450 MHz, at a power density of 1 mW/cm2 and specific absorption rate of 1.2 mW/g, continuous waves (CW) or pulsed waves (PW), 2.5 h/day, 6 sessions/week until death (up to 690 h of irradiation), has been studied in black C57/6J mice with B16 melanoma. The results show that no significant effects are observed on tumor development or on survival times compared to controls, or between CW- and PW-treated animals.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionno_effect
PopulationBlack C57/6J mice with B16 melanoma
Sample sizeNot supplied
Exposuremicrowave · 2450 MHz · 0.0012 W/kg · 2.5 h/day, 6 sessions/week until death (up to 690 h)
Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

In black C57/6J mice with B16 melanoma, low-level 2,450 MHz microwave exposure (1 mW/cm2; SAR 1.2 mW/g) for up to 690 hours showed no significant effects on tumor development or survival compared with controls. No significant differences were observed between continuous-wave and pulsed-wave exposure.

Outcomes measured

  • tumor development
  • survival time

Limitations

  • Sample size not reported in the provided abstract/metadata.
  • Details of randomization/blinding and tumor assessment methods not reported in the provided abstract/metadata.
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": 2450,
    "sar_wkg": 0.0012,
    "duration": "2.5 h/day, 6 sessions/week until death (up to 690 h)"
  },
  "population": "Black C57/6J mice with B16 melanoma",
  "sample_size": null,
  "outcomes": [
    "tumor development",
    "survival time"
  ],
  "main_findings": "In black C57/6J mice with B16 melanoma, low-level 2,450 MHz microwave exposure (1 mW/cm2; SAR 1.2 mW/g) for up to 690 hours showed no significant effects on tumor development or survival compared with controls. No significant differences were observed between continuous-wave and pulsed-wave exposure.",
  "effect_direction": "no_effect",
  "limitations": [
    "Sample size not reported in the provided abstract/metadata.",
    "Details of randomization/blinding and tumor assessment methods not reported in the provided abstract/metadata."
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "microwave radiation",
    "2450 MHz",
    "power density",
    "specific absorption rate",
    "continuous wave",
    "pulsed wave",
    "C57/6J mice",
    "B16 melanoma",
    "tumor development",
    "survival"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1002/bem.2250090110
PubMed: 3345211

Read the original paper →

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