Effects of 2450 MHz microwave radiation during the gestational period on the postnatal hematology of rats.

Cell biophysics · 1983 · Mixed · Low evidence

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MixedLow evidencePaper 5951

Study snapshot

PublicationCell biophysics · 1983

Study typeanimal

Reported directionMixed

Evidence ratingLow

Abstract

Pregnant Sprague-Dawley rats were exposed to 2.45 GHz CW radiation for 3 h daily from day 4 through day 20 of pregnancy at an average power density of 10.3 mW/cm2. At 2, 10, 20, and 30 d postpartum, several aspects of peripheral blood hematology of male and female pups were examined. No effects were noted on pregnancy rate or litter size; however, pup weight was reduced. Also, the white blood cell numbers were lower in male and female pups exposed to microwave radiation and the differential cell counts were altered in the female pups at 10 d postpartum. At 30 d of age, no differences were noted between the sham and exposed pups for any of the hematologic variables examined.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal

Effect directionmixed

PopulationPregnant Sprague-Dawley rats and their male and female pups

Sample sizeNot supplied

Exposuremicrowave · 2450 MHz · 3 h daily from gestation day 4 through day 20

Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Gestational exposure to 2.45 GHz continuous-wave radiation (average power density 10.3 mW/cm2) did not affect pregnancy rate or litter size, but pup weight was reduced. White blood cell numbers were lower in exposed male and female pups, and differential cell counts were altered in female pups at 10 days postpartum. By 30 days postpartum, no differences were observed between sham and exposed pups for hematologic variables examined.

Outcomes measured

pregnancy rate
litter size
pup weight
white blood cell count
differential cell counts
peripheral blood hematology (multiple variables)

Limitations

Sample size not reported in abstract.
SAR and dosimetry beyond average power density not reported in abstract.
Hematologic effects appeared transient (no differences at 30 days postpartum).

View raw extracted JSON

{
  "study_type": "animal",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": 2450,
    "sar_wkg": null,
    "duration": "3 h daily from gestation day 4 through day 20"
  },
  "population": "Pregnant Sprague-Dawley rats and their male and female pups",
  "sample_size": null,
  "outcomes": [
    "pregnancy rate",
    "litter size",
    "pup weight",
    "white blood cell count",
    "differential cell counts",
    "peripheral blood hematology (multiple variables)"
  ],
  "main_findings": "Gestational exposure to 2.45 GHz continuous-wave radiation (average power density 10.3 mW/cm2) did not affect pregnancy rate or litter size, but pup weight was reduced. White blood cell numbers were lower in exposed male and female pups, and differential cell counts were altered in female pups at 10 days postpartum. By 30 days postpartum, no differences were observed between sham and exposed pups for hematologic variables examined.",
  "effect_direction": "mixed",
  "limitations": [
    "Sample size not reported in abstract.",
    "SAR and dosimetry beyond average power density not reported in abstract.",
    "Hematologic effects appeared transient (no differences at 30 days postpartum)."
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "2.45 GHz",
    "2450 MHz",
    "microwave radiation",
    "continuous wave",
    "gestational exposure",
    "Sprague-Dawley rats",
    "postnatal",
    "hematology",
    "white blood cells",
    "pup weight"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1007/bf02788585
PubMed: 6190565

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