[Low intensity electromagnetic fields produce a wave of calcium in the fibroblasts].

{
  "study_type": "in_vitro",
  "exposure": {
    "band": null,
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": null,
  "sample_size": null,
  "outcomes": [
    "Ca2+ wave in human fibroblasts",
    "Number of excited cells (dose-response with EMF intensity)",
    "Dependence on extracellular Ca2+",
    "Dependence on active tyrosine kinases",
    "Dependence on phospholipase C gamma",
    "Requirement for a dialysable serum factor for cellular activation"
  ],
  "main_findings": "Human fibroblasts showed a Ca2+ wave after irradiation with a low-intensity EMF (100–900 microT). The number of excited cells increased proportionally with EMF intensity in this range, and induction required a dialysable serum factor and depended on extracellular Ca2+, active tyrosine kinases, and phospholipase C gamma.",
  "effect_direction": "mixed",
  "limitations": [
    "Frequency of the electromagnetic field not reported in the abstract",
    "Exposure duration not reported in the abstract",
    "No sample size or replication details provided in the abstract",
    "In vitro findings; no direct human health outcomes reported"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "electromagnetic field",
    "low intensity",
    "microtesla",
    "human fibroblasts",
    "calcium wave",
    "Fluo-3",
    "confocal microscopy",
    "tyrosine kinases",
    "phospholipase C gamma",
    "extracellular calcium",
    "serum factor"
  ],
  "suggested_hubs": []
}