[Application of impulse complex modulated electromagnetic fields in management of patients with diabetic polyneuropathy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2002 · Benefit · Insufficient evidence

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BenefitInsufficient evidencePaper 5286

Study snapshot

PublicationZhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2002

Study typeother

Reported directionBenefit

Evidence ratingInsufficient

Abstract

One hundred and twenty-one patients with diabetic polyneuropathy (DP) underwent a clinical and electroneuromyographic investigation before and after treatment with impulse complex modulated electromagnetic fields (ICM EMF) of varying frequency (100 and 10 Hz). Based on TSS and NIS LL scale tests, a correlation between the progression and occurrence of the basic subjective and objective signs of the disease and a DP stage was revealed. The alterations of segmental and peripheral neuromotor system manifesting in reduction of muscular bioelectrical activity, impulse conduction velocities in efferent fibers of peripheral nerves and maximal M-response amplitude were found to be related to DP stage and diabetes mellitus duration. A decrease of H-reflex amplitude and Hmax/Mmax ratio measured in crural muscles proved to be the earliest and most significant electroneuromyographic DP trait. ICM EMF application promotes a regression of DP basic clinical symptoms, an improvement of conduction function of peripheral nerves and 1a afferents state as well as a reflex excitability of functionally different spinal motoneurons. Therapeutic efficacy of a 10 Hz ICM EMF, particularly for DP primary stages and diabetes mellitus up to 10-year duration, was proved.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeother

Effect directionbenefit

PopulationPatients with diabetic polyneuropathy

Sample size121

ExposureNot supplied

Evidence strengthInsufficientConfidence: 66% · Peer reviewed: yes

Main findings

In 121 patients with diabetic polyneuropathy assessed before and after treatment, application of impulse complex modulated electromagnetic fields (100 Hz and 10 Hz) was reported to promote regression of basic clinical symptoms and improvement in several electroneuromyographic measures (including conduction function of peripheral nerves and reflex-related measures). The abstract states therapeutic efficacy was shown for 10 Hz exposure, particularly in early-stage diabetic polyneuropathy and diabetes duration up to 10 years.

Outcomes measured

Clinical symptoms of diabetic polyneuropathy
TSS score
NIS LL score
Electroneuromyographic measures (muscular bioelectrical activity, impulse conduction velocities in efferent fibers of peripheral nerves, maximal M-response amplitude)
H-reflex amplitude
Hmax/Mmax ratio
Conduction function of peripheral nerves
State of Ia afferents
Reflex excitability of spinal motoneurons

Limitations

No control or comparison group described in the abstract
Randomization/blinding not described
Exposure parameters beyond frequency (e.g., intensity, duration, dosing) not reported
Follow-up duration not reported

View raw extracted JSON

{
  "study_type": "other",
  "exposure": {
    "band": null,
    "source": "therapeutic electromagnetic field device (impulse complex modulated EMF)",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Patients with diabetic polyneuropathy",
  "sample_size": 121,
  "outcomes": [
    "Clinical symptoms of diabetic polyneuropathy",
    "TSS score",
    "NIS LL score",
    "Electroneuromyographic measures (muscular bioelectrical activity, impulse conduction velocities in efferent fibers of peripheral nerves, maximal M-response amplitude)",
    "H-reflex amplitude",
    "Hmax/Mmax ratio",
    "Conduction function of peripheral nerves",
    "State of Ia afferents",
    "Reflex excitability of spinal motoneurons"
  ],
  "main_findings": "In 121 patients with diabetic polyneuropathy assessed before and after treatment, application of impulse complex modulated electromagnetic fields (100 Hz and 10 Hz) was reported to promote regression of basic clinical symptoms and improvement in several electroneuromyographic measures (including conduction function of peripheral nerves and reflex-related measures). The abstract states therapeutic efficacy was shown for 10 Hz exposure, particularly in early-stage diabetic polyneuropathy and diabetes duration up to 10 years.",
  "effect_direction": "benefit",
  "limitations": [
    "No control or comparison group described in the abstract",
    "Randomization/blinding not described",
    "Exposure parameters beyond frequency (e.g., intensity, duration, dosing) not reported",
    "Follow-up duration not reported"
  ],
  "evidence_strength": "insufficient",
  "confidence": 0.66,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "diabetic polyneuropathy",
    "impulse complex modulated electromagnetic fields",
    "ICM EMF",
    "10 Hz",
    "100 Hz",
    "electroneuromyography",
    "H-reflex",
    "nerve conduction",
    "TSS",
    "NIS LL"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: Not supplied
PubMed: 12520773

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