[Effect of 900 MHz electromagnetic fields on the expression of GABA receptor of cerebral cortical neurons in postnatal rats].

Wei sheng yan jiu = Journal of hygiene research · 2005 · Mixed · Low evidence

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MixedLow evidencePaper 5157

Exposed neurons showed significant changes in GABA receptor expression (P < 0.01). The authors report a power “window” effect.

Study snapshot

PublicationWei sheng yan jiu = Journal of hygiene research · 2005

Study typeanimal

Reported directionMixed

Evidence ratingLow

Abstract

OBJECTIVE: To investigate the effects of 900 MHz microwave electromagnetic fields (EMF) on the expression of neurotransmitter GABA receptor of cerebral cortical neurons in postnatal rats. METHODS: Neurons were exposed to 900 MHz continuous microwave EMF (SAR = 1.15 - 3.22mW/g) for 2 hours per day in 6 consecutive days and for 12 hours at one time. GABA receptor was chosen to be the biological end. RESULTS: Significant changes had been observed in exposed neurons in the expression of GABA receptor. (P < 0.01) . CONCLUSION: The expression of GABA receptor of neurons were significantly regulated by 900 MHz microwave, and a power "window" effect was observed in the exposed neurons.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal

Effect directionmixed

PopulationPostnatal rats (cerebral cortical neurons)

Sample sizeNot supplied

ExposureRF · 900 MHz · 2 hours/day for 6 consecutive days; and 12 hours at one time

Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

Exposed neurons showed significant changes in GABA receptor expression (P < 0.01). The authors report a power “window” effect.

Outcomes measured

GABA receptor expression in cerebral cortical neurons

Limitations

Sample size not reported in abstract
Direction of change in GABA receptor expression not specified
Exposure setup details beyond frequency, SAR range, and duration not provided

View raw extracted JSON

{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": null,
    "frequency_mhz": 900,
    "sar_wkg": null,
    "duration": "2 hours/day for 6 consecutive days; and 12 hours at one time"
  },
  "population": "Postnatal rats (cerebral cortical neurons)",
  "sample_size": null,
  "outcomes": [
    "GABA receptor expression in cerebral cortical neurons"
  ],
  "main_findings": "Exposed neurons showed significant changes in GABA receptor expression (P < 0.01). The authors report a power “window” effect.",
  "effect_direction": "mixed",
  "limitations": [
    "Sample size not reported in abstract",
    "Direction of change in GABA receptor expression not specified",
    "Exposure setup details beyond frequency, SAR range, and duration not provided"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "900 MHz",
    "microwave",
    "RF EMF",
    "SAR",
    "GABA receptor",
    "cerebral cortex",
    "neurons",
    "postnatal rats",
    "power window effect"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: Not supplied
PubMed: 16329593

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