Effects of time-variant extremely low-frequency (ELF) electromagnetic fields (EMF) on cholinesterase activity in Dictyostelium discoideum (Protista).

Chemico-biological interactions · 2005 · Mixed · Low evidence

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MixedLow evidencePaper 5155

Exposure of single-cell amoebae to an extremely low-frequency electromagnetic field (300 microT, 50 Hz) for 1 to 48 hours affected propionylcholinesterase (PrChE) activity.

Study snapshot

PublicationChemico-biological interactions · 2005

Study typeanimal

Reported directionMixed

Evidence ratingLow

Abstract

Recently, we detected propionylcholinesterase (PrChE) activity in single-cell amoebae of Dictyostelium discoideum using cytochemical, electrophoretic, and spectrophotometric methods. The involvement of this enzyme activity in cell-cell and cell-environment interactions was suggested. In this work, we found that exposure of single-cell amoebae to an extremely low-frequency electromagnetic fields (ELF-EMF) of 300 microT, 50 Hz, from 1 h up to 48 h at 21 +/- 1 degrees C affected PrChE activity.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal

Effect directionmixed

PopulationSingle-cell amoebae of Dictyostelium discoideum (Protista)

Sample sizeNot supplied

ExposureELF · 0.05 MHz · 1 h to 48 h

Evidence strengthLowConfidence: 72% · Peer reviewed: yes

Main findings

Exposure of single-cell amoebae to an extremely low-frequency electromagnetic field (300 microT, 50 Hz) for 1 to 48 hours affected propionylcholinesterase (PrChE) activity.

Outcomes measured

Propionylcholinesterase (PrChE) activity

Limitations

No direction or magnitude of the PrChE activity change is reported in the abstract.
Sample size and experimental design details are not provided in the abstract.
Only one field strength and frequency are described in the abstract.

View raw extracted JSON

{
  "study_type": "animal",
  "exposure": {
    "band": "ELF",
    "source": null,
    "frequency_mhz": 0.05,
    "sar_wkg": null,
    "duration": "1 h to 48 h"
  },
  "population": "Single-cell amoebae of Dictyostelium discoideum (Protista)",
  "sample_size": null,
  "outcomes": [
    "Propionylcholinesterase (PrChE) activity"
  ],
  "main_findings": "Exposure of single-cell amoebae to an extremely low-frequency electromagnetic field (300 microT, 50 Hz) for 1 to 48 hours affected propionylcholinesterase (PrChE) activity.",
  "effect_direction": "mixed",
  "limitations": [
    "No direction or magnitude of the PrChE activity change is reported in the abstract.",
    "Sample size and experimental design details are not provided in the abstract.",
    "Only one field strength and frequency are described in the abstract."
  ],
  "evidence_strength": "low",
  "confidence": 0.72,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "extremely low-frequency",
    "ELF-EMF",
    "50 Hz",
    "300 microT",
    "Dictyostelium discoideum",
    "amoebae",
    "propionylcholinesterase",
    "cholinesterase activity"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1016/j.cbi.2005.10.047
PubMed: 16425446

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