Microneedle array for measuring wound generated electric fields.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference · 2006 · Unclear · Insufficient evidence

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UnclearInsufficient evidencePaper 3457

A fabricated microneedle array was used to measure transdermal skin potentials near superficial wounds in human subjects. Recordings confirmed a lateral electric field in human skin that decays with distance from the wound edge and is directed toward the woun…

Study snapshot

PublicationConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference · 2006
Study typeengineering
Reported directionUnclear
Evidence ratingInsufficient

Abstract

A microneedle array has been fabricated and applied to the measurement of transdermal skin potentials in human subjects. Potential changes were recorded in the vicinity of superficial wounds, confirming the generation of a lateral electric field in human skin. The measured electric field decays with distance from the wound edge, and is directed towards the wound. The measurement of endogenous fields in skin is a prelude to the study of the therapeutic efficacy of applied electric fields to chronic non-healing wounds.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeengineering
Effect directionunclear
PopulationHuman subjects
Sample sizeNot supplied
ExposureNot supplied
Evidence strengthInsufficientConfidence: 74% · Peer reviewed: yes

Main findings

A fabricated microneedle array was used to measure transdermal skin potentials near superficial wounds in human subjects. Recordings confirmed a lateral electric field in human skin that decays with distance from the wound edge and is directed toward the wound.

Outcomes measured

  • Transdermal skin potentials
  • Electric field magnitude/direction near superficial wounds
  • Spatial decay of electric field with distance from wound edge

Limitations

  • Sample size not reported in abstract
  • No health outcomes or therapeutic effects assessed; measurements only
  • Wounds described as superficial; generalizability to chronic wounds not addressed
View raw extracted JSON
{
  "study_type": "engineering",
  "exposure": {
    "band": null,
    "source": "endogenous (wound-generated electric fields in human skin)",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Human subjects",
  "sample_size": null,
  "outcomes": [
    "Transdermal skin potentials",
    "Electric field magnitude/direction near superficial wounds",
    "Spatial decay of electric field with distance from wound edge"
  ],
  "main_findings": "A fabricated microneedle array was used to measure transdermal skin potentials near superficial wounds in human subjects. Recordings confirmed a lateral electric field in human skin that decays with distance from the wound edge and is directed toward the wound.",
  "effect_direction": "unclear",
  "limitations": [
    "Sample size not reported in abstract",
    "No health outcomes or therapeutic effects assessed; measurements only",
    "Wounds described as superficial; generalizability to chronic wounds not addressed"
  ],
  "evidence_strength": "insufficient",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "microneedle array",
    "transdermal skin potential",
    "endogenous electric field",
    "wound electric field",
    "human skin",
    "bioelectricity",
    "measurement device"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1109/iembs.2006.260205
PubMed: 17947077

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