[Modulation of Ca(2+)-Dependent Proteiolysis under the Action of Weak Low-Frequency Magnetic Fields].

{
  "study_type": "animal",
  "exposure": {
    "band": "ELF",
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Model organisms (fish, whelk)",
  "sample_size": null,
  "outcomes": [
    "Ca(2+)-dependent proteinase activity",
    "Time-dependent inactivation of Ca(2+)-dependent proteinases (minimal exposure time)"
  ],
  "main_findings": "Time-dependent effects of weak low-frequency magnetic fields tuned to parametric resonance for calcium ions were studied in fish and whelk. The dynamics of Ca(2+)-dependent proteinase activity under magnetic-field exposure were determined, and a minimal exposure time to achieve inactivation of these proteinases was identified.",
  "effect_direction": "mixed",
  "limitations": [
    "No magnetic-field parameters (e.g., frequency, intensity) reported in the abstract",
    "Exposure duration details not provided (only that a minimal time was determined)",
    "Sample size not reported",
    "Outcomes limited to biochemical/proteinase activity measures in model organisms"
  ],
  "evidence_strength": "low",
  "confidence": 0.66,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "weak low-frequency magnetic field",
    "ELF magnetic field",
    "parametric resonance",
    "calcium ions",
    "Ca2+-dependent proteiolysis",
    "proteinases",
    "fish",
    "whelk"
  ],
  "suggested_hubs": [
    {
      "slug": "occupational-exposure",
      "weight": 0.1,
      "reason": "Involves low-frequency magnetic-field exposure, but no clear occupational context is stated."
    }
  ]
}