RF Safe

Wi-Fi radiation (2.4 GHz) causes impaired insulin secretion and increased oxidative stress in rat pancreatic

2018 · Harm · Low evidence

← Research stream
HarmLow evidencePaper 2068

After long-term Wi‑Fi (2.45 GHz) exposure (4 h/day for 45 days), rats had significantly lower weight gain and showed hyperglycemia. Plasma insulin and glucose-stimulated insulin secretion were significantly reduced, with increased lipid peroxidation and decre…

Study snapshot

Publicationmanual · 2018
Study typeanimal
Reported directionHarm
Evidence ratingLow

Abstract

Wi-Fi radiation (2.4 GHz) causes impaired insulin secretion and increased oxidative stress in rat pancreatic islets Masoumi A, Karbalaei N, Mortazavi SMJ, Shabani M. Radiofrequency radiation emitted from Wi-Fi (2.4 GHz) causes impaired insulin secretion and increased oxidative stress in rat pancreatic islets.Int J Radiat Biol. 2018 Jun 18:1-20. doi: 10.1080/09553002.2018.1490039. Abstract PURPOSE: There is a great concern regarding the possible adverse effects of electromagnetic radiation (EMR). This study investigated the effects of EMR induced by Wi-Fi (2.45GHz) on insulin secretion and antioxidant redox systems in the rat pancreas. MATERIALS AND METHODS: Adult male Sprague-Dawley rats in the weight range of 230 to 260 g were divided into control, sham, Wi-Fi exposed groups. After long term exposure (4 h/day for 45 days) to Wi-Fi electromagnetic radiation, plasma levels of glucose and insulin during intraperitoneal glucose tolerance test were measured. Islet insulin secretion and content, lipid peroxidation and antioxidant status in pancreas of rats were determined. RESULTS: Our data showed that the weight gain in the WI-FI exposed group was significantly lower than the control group (p<0.05). Wi-Fi (2.45 GHz) exposed group showed hyperglycemia. Plasma insulin level and glucose- stimulated insulin secretion from pancreatic islet were significantly reduced in the Wi-Fi exposed group. EMR emitted from Wi-Fi caused a significant increase in lipid peroxidation and a significant decrease in GSH level, SOD and GPx activities of the pancreas. CONCLUSION: these data showed that EMR of Wi-Fi leads to hyperglycemia, increased oxidative stress and impaired insulin secretion in the rat pancreatic islets. ncbi.nlm.nih.gov

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionharm
PopulationAdult male Sprague-Dawley rats (230–260 g)
Sample sizeNot supplied
ExposureRF · 2450 MHz · 4 h/day for 45 days
Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

After long-term Wi‑Fi (2.45 GHz) exposure (4 h/day for 45 days), rats had significantly lower weight gain and showed hyperglycemia. Plasma insulin and glucose-stimulated insulin secretion were significantly reduced, with increased lipid peroxidation and decreased pancreatic GSH, SOD, and GPx.

Outcomes measured

  • Body weight gain
  • Plasma glucose (intraperitoneal glucose tolerance test)
  • Plasma insulin (intraperitoneal glucose tolerance test)
  • Glucose-stimulated insulin secretion from pancreatic islets
  • Islet insulin content
  • Lipid peroxidation (pancreas)
  • GSH level (pancreas)
  • SOD activity (pancreas)
  • GPx activity (pancreas)

Limitations

  • Sample size not reported in abstract
  • Specific exposure metrics beyond frequency and duration (e.g., SAR/power density, distance) not reported in abstract
  • Randomization/blinding not described in abstract
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": "wi-fi",
    "frequency_mhz": 2450,
    "sar_wkg": null,
    "duration": "4 h/day for 45 days"
  },
  "population": "Adult male Sprague-Dawley rats (230–260 g)",
  "sample_size": null,
  "outcomes": [
    "Body weight gain",
    "Plasma glucose (intraperitoneal glucose tolerance test)",
    "Plasma insulin (intraperitoneal glucose tolerance test)",
    "Glucose-stimulated insulin secretion from pancreatic islets",
    "Islet insulin content",
    "Lipid peroxidation (pancreas)",
    "GSH level (pancreas)",
    "SOD activity (pancreas)",
    "GPx activity (pancreas)"
  ],
  "main_findings": "After long-term Wi‑Fi (2.45 GHz) exposure (4 h/day for 45 days), rats had significantly lower weight gain and showed hyperglycemia. Plasma insulin and glucose-stimulated insulin secretion were significantly reduced, with increased lipid peroxidation and decreased pancreatic GSH, SOD, and GPx.",
  "effect_direction": "harm",
  "limitations": [
    "Sample size not reported in abstract",
    "Specific exposure metrics beyond frequency and duration (e.g., SAR/power density, distance) not reported in abstract",
    "Randomization/blinding not described in abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "Wi-Fi",
    "2.45 GHz",
    "radiofrequency radiation",
    "rat",
    "pancreatic islets",
    "insulin secretion",
    "hyperglycemia",
    "oxidative stress",
    "lipid peroxidation",
    "GSH",
    "SOD",
    "GPx"
  ],
  "suggested_hubs": [
    {
      "slug": "school-wi-fi",
      "weight": 0.6,
      "reason": "Study examines biological effects of Wi‑Fi (2.45 GHz) exposure."
    }
  ]
}
AI can be wrong. Always verify against the paper.

AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1080/09553002.2018.1490039
PubMed: Not supplied

Read the original paper →

Related papers

← Back to the Research Library