Cell phone use and risk of thyroid cancer: a population-based case-control study in Connecticut

2018 · Mixed · Low evidence

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MixedLow evidencePaper 1973

Study snapshot

Publicationmanual · 2018

Study typecase_control

Reported directionMixed

Evidence ratingLow

Abstract

Cell phone use and risk of thyroid cancer: a population-based case-control study in Connecticut Luo J, Deziel NC, Huang H, Chen Y, Ni X, Ma S, Udelsman R, Zhang Y. Cell phone use and risk of thyroid cancer: a population-based case-control study in Connecticut. Annals of Epidemiology, Published online Oct 29, 2018. doi.org. Abstract Purpose This study aims to investigate the association between cell phone use and thyroid cancer. Methods A population-based case-control study was conducted in Connecticut between 2010 and 2011 including 462 histologically confirmed thyroid cancer cases and 498 population-based controls. Multivariate unconditional logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (95% CI) for associations between cell phone use and thyroid cancer. Results Cell phone use was not associated with thyroid cancer (OR: 1.05, 95% CI: 0.74-1.48). A suggestive increase in risk of thyroid microcarcinoma (tumor size ≤10mm) was observed for long-term and more frequent users. Compared to cell phone non-users, several groups had non-statistically significantly increased risk of thyroid microcarcinoma: individuals who had used a cell phone >15 years (OR: 1.29, 95% CI: 0.83-2.00), who had used a cell phone >2 hours per day (OR: 1.40, 95% CI: 0.83-2.35), who had the most cumulative use hours (OR: 1.58, 95% CI: 0.98-2.54), and who had the most cumulative calls (OR: 1.20, 95% CI: 0.78-1.84). Conclusion This study found no significant association between cell phone use and thyroid cancer. A suggestive elevated risk of thyroid microcarcinoma associated with long-term and more frequent uses warrants further investigation. sciencedirect.com

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typecase_control

Effect directionmixed

PopulationPopulation-based sample in Connecticut (2010–2011): 462 histologically confirmed thyroid cancer cases and 498 population-based controls

Sample size960

ExposureRF

Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Overall cell phone use was not associated with thyroid cancer (OR 1.05, 95% CI 0.74–1.48). For thyroid microcarcinoma, several long-term/more frequent use categories showed non-statistically significant elevated ORs (e.g., >15 years use OR 1.29; >2 hours/day OR 1.40; highest cumulative hours OR 1.58; highest cumulative calls OR 1.20), described as suggestive and warranting further investigation.

Outcomes measured

Thyroid cancer
Thyroid microcarcinoma (tumor size ≤10 mm)

View raw extracted JSON

{
  "study_type": "case_control",
  "exposure": {
    "band": "RF",
    "source": "mobile phone",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Population-based sample in Connecticut (2010–2011): 462 histologically confirmed thyroid cancer cases and 498 population-based controls",
  "sample_size": 960,
  "outcomes": [
    "Thyroid cancer",
    "Thyroid microcarcinoma (tumor size ≤10 mm)"
  ],
  "main_findings": "Overall cell phone use was not associated with thyroid cancer (OR 1.05, 95% CI 0.74–1.48). For thyroid microcarcinoma, several long-term/more frequent use categories showed non-statistically significant elevated ORs (e.g., >15 years use OR 1.29; >2 hours/day OR 1.40; highest cumulative hours OR 1.58; highest cumulative calls OR 1.20), described as suggestive and warranting further investigation.",
  "effect_direction": "mixed",
  "limitations": [],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "cell phone",
    "mobile phone",
    "RF exposure",
    "thyroid cancer",
    "thyroid microcarcinoma",
    "case-control",
    "Connecticut",
    "odds ratio"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1016/j.annepidem.2018.10.004
PubMed: Not supplied

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