Behavioral risk factors of breast cancer in Bangui of Central African Republic: A retrospective case-control study

2017 · Mixed · Low evidence

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MixedLow evidencePaper 2294

Study snapshot

Publicationmanual · 2017

Study typecase_control

Reported directionMixed

Evidence ratingLow

Abstract

Behavioral risk factors of breast cancer in Bangui of Central African Republic: A retrospective case-control study Balekouzou A, Yin P, Afewerky HK, Bekolo C, Pamatika CM, Nambei SW, et al. Behavioral risk factors of breast cancer in Bangui of Central African Republic: A retrospective case-control study. PLoS One. 2017 Feb 8;12(2):e0171154. doi: 10.1371/journal.pone.0171154. Abstract Breast cancer is recognized as a major public health problem in developing countries; however, there is very little evidence of behavioral factors associated with breast cancer risk. This study was conducted to identify lifestyles as risk factors for breast cancer among Central African women. A case-control study was conducted with 174 cases confirmed histologically by the pathology unit of the National Laboratory and 348 age-matched controls. Data collection tools included a questionnaire with interviews and medical records of patients. Data were analyzed using SPSS software version 20. Odd ratio (OR) and 95% confidence intervals (95% CI) were obtained by unconditional logistic regression. In total, 522 women were studied with a mean age of 45.8 (SD = 13.4) years. By unconditional logistic regression model, women with breast cancer were more likely to have attained illiterate and elementary education level [11.23 (95% CI, 4.65-27.14) and 2.40 (95% CI, 1.15-4.99)], married [2.09 (95% CI, 1.18-3.71)], positive family history [2.31 (95% CI, 1.36-3.91)], radiation exposure [8.21 (95% CI, 5.04-13.38)], consumption charcuterie [10.82 (95% CI, 2.39-48.90)], fresh fish consumption [4.26 (95% CI, 1.56-11.65)], groundnut consumption [6.46 (95% CI, 2.57-16.27)], soybean consumption [16.74 (95% CI, 8.03- 39.84)], alcohol [2.53 (95% CI, 1.39-4.60)], habit of keeping money in bras[3.57 (95% CI, 2.24-5.69)], overweight [5.36 (95% CI, 4.46-24.57)] and obesity [3.11(95% CI, 2.39-20.42)]. However, decreased risk of breast cancer was associated with being employed [0.32 (95% CI, 0.19-0.56)], urban residence [0.16 (95% CI, 0.07-0.37)], groundnut oil consumption [0.05 (95% CI, 0.02-0.14)], wine consumption [0.16 (95% CI, 0.09-0.26)], non habit of keeping cell phone in bras [0.56 (95% CI, 0.35-0.89)] and physical activity [0.71(95% CI, 0.14-0.84)]. The study showed that little or no education, marriage, positive family history of cancer, radiation exposure, charcuterie, fresh fish, groundnut, soybean, alcohol, habit of keeping money in bras, overweight and obesity were associated with breast cancer risk among Central African women living in Bangui. Women living in Bangui should be more cautious on the behavioral risk associated with breast cancer. journals.plos.org

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typecase_control

Effect directionmixed

PopulationCentral African women living in Bangui (Central African Republic)

Sample size522

ExposureNot supplied

Evidence strengthLowConfidence: 72% · Peer reviewed: yes

Main findings

In unconditional logistic regression, breast cancer was associated with several factors including radiation exposure (OR 8.21, 95% CI 5.04–13.38) and the habit of keeping money in bras (OR 3.57, 95% CI 2.24–5.69). A decreased risk was reported for the non-habit of keeping a cell phone in bras (OR 0.56, 95% CI 0.35–0.89), along with other factors such as employment, urban residence, and physical activity.

Outcomes measured

Breast cancer risk (case-control status)

Limitations

Retrospective case-control design
Exposure assessment based on questionnaire/interviews and medical records (potential recall/misclassification)

View raw extracted JSON

{
  "study_type": "case_control",
  "exposure": {
    "band": null,
    "source": "mobile phone",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Central African women living in Bangui (Central African Republic)",
  "sample_size": 522,
  "outcomes": [
    "Breast cancer risk (case-control status)"
  ],
  "main_findings": "In unconditional logistic regression, breast cancer was associated with several factors including radiation exposure (OR 8.21, 95% CI 5.04–13.38) and the habit of keeping money in bras (OR 3.57, 95% CI 2.24–5.69). A decreased risk was reported for the non-habit of keeping a cell phone in bras (OR 0.56, 95% CI 0.35–0.89), along with other factors such as employment, urban residence, and physical activity.",
  "effect_direction": "mixed",
  "limitations": [
    "Retrospective case-control design",
    "Exposure assessment based on questionnaire/interviews and medical records (potential recall/misclassification)"
  ],
  "evidence_strength": "low",
  "confidence": 0.72,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "breast cancer",
    "case-control",
    "Bangui",
    "Central African Republic",
    "behavioral risk factors",
    "radiation exposure",
    "cell phone",
    "keeping phone in bra"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1371/journal.pone.0171154
PubMed: Not supplied

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