Effects of Simulated Mobile Phone Electromagnetic Radiation on Fertilization and Embryo Development

2016 · Harm · Low evidence

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HarmLow evidencePaper 1401

Study snapshot

Publicationmanual · 2016

Study typeanimal

Reported directionHarm

Evidence ratingLow

Abstract

Effects of Simulated Mobile Phone Electromagnetic Radiation on Fertilization and Embryo Development Chen H, Qu Z, Liu W. Effects of Simulated Mobile Phone Electromagnetic Radiation on Fertilization and Embryo Development. Fetal Pediatr Pathol. 2016 Dec 16:1-7. Abstract This study investigated the effects of 935-MHz electromagnetic radiation (ER) on fertilization and subsequent embryonic development in mice. Ovulating mice were irradiated at three ER intensities for 4 h/day (d) or 2 h/d for three consecutive days; the ova were then harvested for in vitro fertilization to observe the 6-h fertilization rate (6-FR), 72-h morula rate (72-MR), and 110-h blastula rate (110-BR). Compared with the control group, the 6- FR, 72-MR, and 110-BR were decreased in the low ER intensity group, but the differences were not significant; in the mid- and high-intensity ER groups, 72-MR and 110-BR in the 4 h/d and 2 h/d subgroups were decreased, showing significant differences compared with the control group. Moreover, the comparison between 4 h/d and 2 h/d subgroups showed significant differences. Mid- and high-intensity ER at 935 MHz can reduce the fertilization rate in mice, and reduce the blastulation rate, thus reducing the possibility of embryo implantation. ncbi.nlm.nih.gov Excerpts Electromagnetic radiation devices consisted of four parts: a signal source (with frequency ranging from 935 to 960 MHz and magnetic field strength ranging from -15 db to +15 db), a rectifier (220 VAC/27 VDC; 300 W), a power amplifier, and a specific antenna with a length of 15 cm. The mice were divided into seven groups by using a random table method: low-intensity (2 h/d and 4 h/d subgroups), mid-intensity (570 μW/cm2: 2 h/d and 4 h/d subgroups), high-intensity (1400 μW/cm2: 2 h/d and 4 h/d subgroups), and control groups.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal

Effect directionharm

PopulationOvulating mice (ova harvested for in vitro fertilization)

Sample sizeNot supplied

ExposureRF · 935 MHz · 2 h/day or 4 h/day for three consecutive days

Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Compared with controls, low-intensity exposure showed decreased 6-FR, 72-MR, and 110-BR but differences were not significant. Mid- and high-intensity exposure groups showed significantly decreased 72-MR and 110-BR (in both 2 h/day and 4 h/day subgroups) versus controls, and there were significant differences between the 4 h/day and 2 h/day subgroups. The authors conclude mid- and high-intensity 935 MHz exposure can reduce fertilization and blastulation rates in mice.

Outcomes measured

6-hour fertilization rate (6-FR)
72-hour morula rate (72-MR)
110-hour blastula rate (110-BR)

Limitations

Sample size not reported in provided text
Specific exposure metric for low-intensity group not provided in provided text
SAR not reported; exposure described in μW/cm² for some groups
Study is in mice; relevance to humans not established in provided text

View raw extracted JSON

{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": "mobile phone (simulated)",
    "frequency_mhz": 935,
    "sar_wkg": null,
    "duration": "2 h/day or 4 h/day for three consecutive days"
  },
  "population": "Ovulating mice (ova harvested for in vitro fertilization)",
  "sample_size": null,
  "outcomes": [
    "6-hour fertilization rate (6-FR)",
    "72-hour morula rate (72-MR)",
    "110-hour blastula rate (110-BR)"
  ],
  "main_findings": "Compared with controls, low-intensity exposure showed decreased 6-FR, 72-MR, and 110-BR but differences were not significant. Mid- and high-intensity exposure groups showed significantly decreased 72-MR and 110-BR (in both 2 h/day and 4 h/day subgroups) versus controls, and there were significant differences between the 4 h/day and 2 h/day subgroups. The authors conclude mid- and high-intensity 935 MHz exposure can reduce fertilization and blastulation rates in mice.",
  "effect_direction": "harm",
  "limitations": [
    "Sample size not reported in provided text",
    "Specific exposure metric for low-intensity group not provided in provided text",
    "SAR not reported; exposure described in μW/cm² for some groups",
    "Study is in mice; relevance to humans not established in provided text"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "935 MHz",
    "radiofrequency",
    "simulated mobile phone radiation",
    "mice",
    "fertilization",
    "embryo development",
    "morula",
    "blastula",
    "in vitro fertilization"
  ],
  "suggested_hubs": [
    {
      "slug": "mobile-phones",
      "weight": 0.9,
      "reason": "Simulated mobile phone RF exposure at 935 MHz."
    },
    {
      "slug": "reproductive-health",
      "weight": 0.85,
      "reason": "Assesses fertilization and embryo development outcomes."
    }
  ]
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: Not supplied
PubMed: Not supplied

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