RF Safe

Hepatic injury induced by radio frequency waves emitted from conventional Wi-Fi devices in Wistar rats

Human & experimental toxicology · 2020 · Harm · Low evidence

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HarmLow evidencePaper 1360

Compared with controls, Wi‑Fi (2.45 GHz; averaged whole-body SAR 0.01 W/kg) exposure was reported to cause severe oxidative stress in rat liver, deleterious changes in liver function markers (GOT/GPT), altered molecular structure by FTIR, and severe histologi…

Study snapshot

PublicationHuman & experimental toxicology · 2020
Study typeanimal
Reported directionHarm
Evidence ratingLow

Abstract

Hepatic injury induced by radio frequency waves emitted from conventional Wi-Fi devices in Wistar rats H M Fahmy, F F Mohammed. Hepatic injury induced by radio frequency waves emitted from conventional Wi-Fi devices in Wistar rats. Hum Exp Toxicol. 2020 Aug 7;960327120946470. doi: 10.1177/0960327120946470. Abstract In this study, the impact of standard 2.45 GHz radio frequency source (averaged whole-body specific absorption rate 0.01 W kg-1 24 h-1 daily for 40 consecutive days) on the liver of Wistar female rats was investigated. The rats were randomly divided into control and Wi-Fi-exposed groups. At the end of the exposure, liver samples were dissected from rats. Rats' livers were inspected through the evaluation of some oxidative stress parameters and the evaluation of glutamic oxaloacetic transaminase and glutamic-pyruvic transaminase levels as well as through the molecular investigation using Fourier transform infrared spectroscopy. Histopathological examination in addition to ultrastructure examination was also performed. The present data revealed that Wi-Fi exposure leads to severe oxidative stress in the rat liver. Furthermore, Wi-Fi exposure resulted in deleterious effects in the liver function and alters its molecular structure. Moreover, severe histological and ultrastructural alterations are reported in the hepatic tissues points to hepatotoxic effects induced by Wi-Fi exposure. In conclusion, care must be taken when using Wi-Fi emitting devices due to their severe impact on the liver. Public awareness of the need to decrease exposure time and increase the distance from Wi-Fi exposure sources must be raised wherever possible. pubmed.ncbi.nlm.nih.gov

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionharm
PopulationWistar female rats
Sample sizeNot supplied
ExposureRF · 2450 MHz · 0.01 W/kg · 24 h-1 daily for 40 consecutive days
Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Compared with controls, Wi‑Fi (2.45 GHz; averaged whole-body SAR 0.01 W/kg) exposure was reported to cause severe oxidative stress in rat liver, deleterious changes in liver function markers (GOT/GPT), altered molecular structure by FTIR, and severe histological and ultrastructural alterations consistent with hepatotoxic effects.

Outcomes measured

  • Oxidative stress parameters in liver
  • Glutamic oxaloacetic transaminase (GOT) levels
  • Glutamic-pyruvic transaminase (GPT) levels
  • Fourier transform infrared spectroscopy (molecular structure)
  • Histopathology of hepatic tissue
  • Ultrastructure examination of hepatic tissue

Limitations

  • Sample size not reported in abstract
  • Exposure characterization limited to frequency and averaged whole-body SAR; other dosimetry details not provided in abstract
  • Animal study; generalizability to humans not addressed in abstract
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": "wi-fi",
    "frequency_mhz": 2450,
    "sar_wkg": 0.01,
    "duration": "24 h-1 daily for 40 consecutive days"
  },
  "population": "Wistar female rats",
  "sample_size": null,
  "outcomes": [
    "Oxidative stress parameters in liver",
    "Glutamic oxaloacetic transaminase (GOT) levels",
    "Glutamic-pyruvic transaminase (GPT) levels",
    "Fourier transform infrared spectroscopy (molecular structure)",
    "Histopathology of hepatic tissue",
    "Ultrastructure examination of hepatic tissue"
  ],
  "main_findings": "Compared with controls, Wi‑Fi (2.45 GHz; averaged whole-body SAR 0.01 W/kg) exposure was reported to cause severe oxidative stress in rat liver, deleterious changes in liver function markers (GOT/GPT), altered molecular structure by FTIR, and severe histological and ultrastructural alterations consistent with hepatotoxic effects.",
  "effect_direction": "harm",
  "limitations": [
    "Sample size not reported in abstract",
    "Exposure characterization limited to frequency and averaged whole-body SAR; other dosimetry details not provided in abstract",
    "Animal study; generalizability to humans not addressed in abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "Wi-Fi",
    "2.45 GHz",
    "radiofrequency",
    "SAR",
    "liver",
    "hepatic injury",
    "oxidative stress",
    "GOT",
    "GPT",
    "FTIR",
    "histopathology",
    "ultrastructure",
    "Wistar rats"
  ],
  "suggested_hubs": [
    {
      "slug": "school-wi-fi",
      "weight": 0.6,
      "reason": "Study examines biological effects from conventional Wi‑Fi device emissions (2.45 GHz)."
    }
  ]
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1177/0960327120946470
PubMed: 32762465

Read the original paper →

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