RF Safe

Impact of 864 MHz or 935 MHz radiofrequency microwave radiation on the basic growth parameters of V79 cell line.

Acta biologica Hungarica · 2008 · Mixed · Low evidence

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MixedLow evidencePaper 6478

V79 cells exposed to 864 MHz (SAR 0.08 W/kg) showed significantly altered growth 72 hours after 2- and 3-hour exposures (p<0.05). Cells exposed to 935 MHz (SAR 0.12 W/kg) showed a similar significant growth effect 72 hours after 3-hour exposure (p<0.05). Colo…

Study snapshot

PublicationActa biologica Hungarica · 2008
Study typein_vitro
Reported directionMixed
Evidence ratingLow

Abstract

The aim of this study was to evaluate and compare the influence of 864 MHz and 935 MHz radiofrequency/microwave (RF/MW) fields on the growth, colony-forming ability, and viability of V79 cells (continuous line). Cell samples with 1 x 10(4) V79 cells each, were exposed to continuous wave frequencies of 864 MHz and 935 MHz for 1, 2 and 3 hours. Exposed samples were matched with unexposed control samples. Specific absorption rate (SAR) was 0.08 W/kg for the 864 MHz or 0.12 W/kg for the 935 MHz field. Cell growth and viability were determined by counting cells every day for five days after exposure. Colony-forming ability was assessed by counting colonies seven days after exposure. The growth of the 864 MHz-irradiated cells was significant after two- and three-hour exposure 72 hours after irradiation (p < 0.05). The similar was observed 72 hours after exposure for cells exposed to 935 MHz microwaves for three hours (p <0.05). Colony-forming ability and cell viability in V79 cells exposed to 864 MHz or 935 MHz microwaves did not significantly differ from control cells. The two applied RF/MW fields showed similar effects on the growth, colony-forming ability and viability of V79 cells. Cell growth impact was time-dependent for both fields.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typein_vitro
Effect directionmixed
PopulationV79 cells (continuous cell line)
Sample sizeNot supplied
ExposureRF · 1, 2, and 3 hours
Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

V79 cells exposed to 864 MHz (SAR 0.08 W/kg) showed significantly altered growth 72 hours after 2- and 3-hour exposures (p<0.05). Cells exposed to 935 MHz (SAR 0.12 W/kg) showed a similar significant growth effect 72 hours after 3-hour exposure (p<0.05). Colony-forming ability and viability did not significantly differ from controls for either frequency.

Outcomes measured

  • cell growth
  • colony-forming ability
  • cell viability

Limitations

  • Sample size not reported in abstract.
  • Direction of the growth change (increase vs decrease) is not specified in the abstract.
  • Only one cell line and short-term endpoints (up to 7 days) are described.
View raw extracted JSON
{
  "study_type": "in_vitro",
  "exposure": {
    "band": "RF",
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": "1, 2, and 3 hours"
  },
  "population": "V79 cells (continuous cell line)",
  "sample_size": null,
  "outcomes": [
    "cell growth",
    "colony-forming ability",
    "cell viability"
  ],
  "main_findings": "V79 cells exposed to 864 MHz (SAR 0.08 W/kg) showed significantly altered growth 72 hours after 2- and 3-hour exposures (p<0.05). Cells exposed to 935 MHz (SAR 0.12 W/kg) showed a similar significant growth effect 72 hours after 3-hour exposure (p<0.05). Colony-forming ability and viability did not significantly differ from controls for either frequency.",
  "effect_direction": "mixed",
  "limitations": [
    "Sample size not reported in abstract.",
    "Direction of the growth change (increase vs decrease) is not specified in the abstract.",
    "Only one cell line and short-term endpoints (up to 7 days) are described."
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "radiofrequency",
    "microwave",
    "864 MHz",
    "935 MHz",
    "SAR",
    "V79",
    "cell growth",
    "colony formation",
    "cell viability",
    "in vitro"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1556/abiol.59.2008.1.6
PubMed: 18401946

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