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Circulating antibody response of mice exposed to 9-GHz pulsed microwave radiation.

Bioelectromagnetics · 1986 · No effect · Low evidence

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No effectLow evidencePaper 6205

Circulating antibody titers in microwave-exposed mice were not significantly different from sham-irradiated mice, and no differences were observed in analyzed hematological parameters under the stated exposure conditions.

Study snapshot

PublicationBioelectromagnetics · 1986
Study typeanimal
Reported directionNo effect
Evidence ratingLow

Abstract

Female CD-1 mice immunized against the bacterium Streptococcus pneumoniae type III were exposed to 9-GHz pulsed microwaves (pulse repetition rate 970-1,000, pulse width 1.0 microseconds, peak power 1 W/cm2) at an average incident power density of 1 mW/cm2 (calculated SAR congruent to 0.47 W/kg) for 2 h per day for 5 days. Circulating antibody titers for the microwave-exposed animals were not significantly different from those of the sham-irradiated animals, and there were no differences in any of the hematological parameters analyzed, indicating that 9-GHz pulsed microwaves at 1 mW/cm2 do not alter the immune response of mice immunized against S pneumoniae.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionno_effect
PopulationFemale CD-1 mice immunized against Streptococcus pneumoniae type III
Sample sizeNot supplied
Exposuremicrowave · 9000 MHz · 0.47 W/kg · 2 h/day for 5 days
Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Circulating antibody titers in microwave-exposed mice were not significantly different from sham-irradiated mice, and no differences were observed in analyzed hematological parameters under the stated exposure conditions.

Outcomes measured

  • Circulating antibody titers
  • Hematological parameters

Limitations

  • Sample size not reported in the provided abstract/metadata
  • Exposure described as incident power density; internal dose characterization beyond calculated SAR is not detailed
  • Short exposure duration (5 days) and limited follow-up information not described
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": 9000,
    "sar_wkg": 0.47,
    "duration": "2 h/day for 5 days"
  },
  "population": "Female CD-1 mice immunized against Streptococcus pneumoniae type III",
  "sample_size": null,
  "outcomes": [
    "Circulating antibody titers",
    "Hematological parameters"
  ],
  "main_findings": "Circulating antibody titers in microwave-exposed mice were not significantly different from sham-irradiated mice, and no differences were observed in analyzed hematological parameters under the stated exposure conditions.",
  "effect_direction": "no_effect",
  "limitations": [
    "Sample size not reported in the provided abstract/metadata",
    "Exposure described as incident power density; internal dose characterization beyond calculated SAR is not detailed",
    "Short exposure duration (5 days) and limited follow-up information not described"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "mouse",
    "CD-1",
    "microwave",
    "9 GHz",
    "pulsed",
    "SAR",
    "immune response",
    "antibody titer",
    "Streptococcus pneumoniae",
    "hematology"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1002/bem.2250070110
PubMed: 3730005

Read the original paper →

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