Effects of 2.45 GHz microwaves on meiotic chromosomes of male CBA/CAY mice.
← Research streamMale mice exposed to continuous 2.45 GHz microwaves showed chain translocations at diakinesis/metaphase I; translocation yield increased with exposure and varied nonlinearly with dose rate. Increased incidence of univalents was reported after exposure at 10 a…
Study snapshot
Abstract
Male CBA/CAY mice were exposed daily (6 days a week) for 30 minutes in an environmentally controlled waveguide to continuous 2.45 GHz microwave radiation for 2 weeks at average whole body absorbed dose rates of 0.05, 0.5, 10, and 20 mW/g. Shan exposed animals served as controls. Chain translocations were observed at diakinesis at metaphase I in microwave exposed animals. The yield of translocations increased with exposure, and varied nonlinearly with dose rate. An increase in incidence of univalents was seen after exposure at 10 and 20 mW/g. The findings are interpreted to indicate interference with normal spermatogenesis during the exposure period.
AI evidence extraction
Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.
Main findings
Male mice exposed to continuous 2.45 GHz microwaves showed chain translocations at diakinesis/metaphase I; translocation yield increased with exposure and varied nonlinearly with dose rate. Increased incidence of univalents was reported after exposure at 10 and 20 mW/g.
Outcomes measured
- Meiotic chromosome abnormalities (chain translocations at diakinesis/metaphase I)
- Incidence of univalents
- Spermatogenesis interference (interpretation)
Limitations
- Sample size not reported in abstract
- Exposure metric reported as absorbed dose rate (mW/g) without explicit SAR conversion in W/kg
- Details on randomization/blinding and statistical methods not provided in abstract
View raw extracted JSON
{
"study_type": "animal",
"exposure": {
"band": "microwave",
"source": null,
"frequency_mhz": 2450,
"sar_wkg": null,
"duration": "30 minutes daily (6 days/week) for 2 weeks"
},
"population": "Male CBA/CAY mice",
"sample_size": null,
"outcomes": [
"Meiotic chromosome abnormalities (chain translocations at diakinesis/metaphase I)",
"Incidence of univalents",
"Spermatogenesis interference (interpretation)"
],
"main_findings": "Male mice exposed to continuous 2.45 GHz microwaves showed chain translocations at diakinesis/metaphase I; translocation yield increased with exposure and varied nonlinearly with dose rate. Increased incidence of univalents was reported after exposure at 10 and 20 mW/g.",
"effect_direction": "harm",
"limitations": [
"Sample size not reported in abstract",
"Exposure metric reported as absorbed dose rate (mW/g) without explicit SAR conversion in W/kg",
"Details on randomization/blinding and statistical methods not provided in abstract"
],
"evidence_strength": "low",
"confidence": 0.78,
"peer_reviewed_likely": "yes",
"keywords": [
"2.45 GHz",
"microwave radiation",
"mouse",
"meiotic chromosomes",
"chain translocations",
"univalents",
"spermatogenesis",
"waveguide",
"absorbed dose rate"
],
"suggested_hubs": []
}AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.
Identifiers and source
DOI: 10.1093/oxfordjournals.jhered.a110027
PubMed: 3980975
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