A New Treatment for Stretch Marks and Skin Ptosis with Electromagnetic Fields and Negative Pressure: A Clinical and Histological Study.

Journal of cutaneous and aesthetic surgery · 2021 · Benefit · Very low evidence

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BenefitVery low evidencePaper 5673

In 60 women receiving 6 or 8 weekly V-EMF sessions, biopsies were reported to show tissue reorganization/restoration with new collagen and elastin, basement membrane reorganization, and correct melanocyte positioning. Patients were reported as highly satisfie…

Study snapshot

PublicationJournal of cutaneous and aesthetic surgery · 2021
Study typeother
Reported directionBenefit
Evidence ratingVery low

Abstract

BACKGROUND: Stretch marks (SM) are nowadays the most common aesthetic pathology of the body; in the XX century, it mainly affected pregnant women, while today it also affects teenagers during puberty, boys and girls without distinction. The aim of this study was to evaluate possible variations in the histological structure of the skin-in terms of quality/quantity of the extracellular matrix and of the collagen and elastic fibers-following the electromagnetic fields and negative pressure (V-EMF) treatment as regards hypotonia and SMs. MATERIALS AND METHODS: For the current study, 60 women, aged between 25 and 45, were examined. All of them presented deep, white or pearly white colored SMs having had them for between 12 and 25 years. These were documented, asking patients their level of satisfaction, through pictures and biopsies. All patients underwent a cycle of 6 or 8 weekly sessions; everyone was highly satisfied with the results obtained. RESULTS: Biopsies proved that the tissue was reorganized and restored to the original volume, characterized by the production of new, high-quality collagen and elastin molecules, by the reorganization of the basement membrane and by the correct positioning of the melanocytes. No side effects were observed during the treatments. This synergy stands as the most suitable treatment of striae rubra and alba. CONCLUSION: V-EMF enhances the keratinocyte migration base, melanocytes, and promotes neoangiogenesis with the result of improvement in the SM.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeother
Effect directionbenefit
PopulationWomen aged 25–45 with long-standing stretch marks (12–25 years)
Sample size60
Exposure6 or 8 weekly sessions
Evidence strengthVery lowConfidence: 72% · Peer reviewed: yes

Main findings

In 60 women receiving 6 or 8 weekly V-EMF sessions, biopsies were reported to show tissue reorganization/restoration with new collagen and elastin, basement membrane reorganization, and correct melanocyte positioning. Patients were reported as highly satisfied and no side effects were observed.

Outcomes measured

  • Histological changes in skin extracellular matrix
  • Collagen production/quality
  • Elastin production/quality
  • Basement membrane reorganization
  • Melanocyte positioning
  • Patient satisfaction
  • Adverse effects/side effects

Limitations

  • No control or comparison group described in the abstract
  • Randomization/blinding not described
  • Electromagnetic field exposure parameters (e.g., frequency, intensity, SAR) not reported
  • Outcome measures and satisfaction assessment methods not detailed in the abstract
View raw extracted JSON
{
  "study_type": "other",
  "exposure": {
    "band": null,
    "source": "clinical aesthetic device (electromagnetic fields) with negative pressure (V-EMF)",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": "6 or 8 weekly sessions"
  },
  "population": "Women aged 25–45 with long-standing stretch marks (12–25 years)",
  "sample_size": 60,
  "outcomes": [
    "Histological changes in skin extracellular matrix",
    "Collagen production/quality",
    "Elastin production/quality",
    "Basement membrane reorganization",
    "Melanocyte positioning",
    "Patient satisfaction",
    "Adverse effects/side effects"
  ],
  "main_findings": "In 60 women receiving 6 or 8 weekly V-EMF sessions, biopsies were reported to show tissue reorganization/restoration with new collagen and elastin, basement membrane reorganization, and correct melanocyte positioning. Patients were reported as highly satisfied and no side effects were observed.",
  "effect_direction": "benefit",
  "limitations": [
    "No control or comparison group described in the abstract",
    "Randomization/blinding not described",
    "Electromagnetic field exposure parameters (e.g., frequency, intensity, SAR) not reported",
    "Outcome measures and satisfaction assessment methods not detailed in the abstract"
  ],
  "evidence_strength": "very_low",
  "confidence": 0.72,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "stretch marks",
    "striae",
    "skin ptosis",
    "electromagnetic fields",
    "negative pressure",
    "V-EMF",
    "histology",
    "collagen",
    "elastin",
    "aesthetic treatment"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.4103/jcas.jcas_122_20
PubMed: 34566367

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