Effects of pulsed magnetic fields in the therapy of osteoporosis induced by ovariectomy in the rat.

Bollettino della Societa italiana di biologia sperimentale · 1993 · Benefit · Low evidence

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BenefitLow evidencePaper 5470

In ovariectomized female rats treated 1 hour/day for 4 months with 50 Hz pulsed magnetic fields, 30 Gauss maximum intensity slowed bone mass loss to within about 10%. With 70 Gauss maximum intensity, no significant bone mass loss was observed.

Study snapshot

PublicationBollettino della Societa italiana di biologia sperimentale · 1993

Study typeanimal

Reported directionBenefit

Evidence ratingLow

Abstract

This paper presents preliminary results on the effects of pulsed electromagnetic fields (EMF) in the therapy of post menopausal osteoporosis induced by ovariectomy in female rats aged ten months. In particular, the effects of the intensity of pulsed EMF applied at constant frequency has been studied. Magnetic fields pulsed at 50 Hz were used having a positive sinusoidal wave form with a maximum intensity of 30 and 70 Gauss. Treatment lasting one hour per day for 4 months showed that the pulsed EMF with 30 Gauss of maximum intensity are able to slow down the bone mass loss, keeping it within some 10%; with pulsed EMF with 70 Gauss of maximum intensity, instead, no significant bone mass loss was observed.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal

Effect directionbenefit

PopulationFemale rats aged ten months with post-menopausal osteoporosis induced by ovariectomy

Sample sizeNot supplied

ExposureELF · 0.05 MHz · 1 hour/day for 4 months

Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

Outcomes measured

Bone mass loss (bone mass)

Limitations

Preliminary results
Sample size not reported in abstract
Details of study design and outcome measurement methods not reported in abstract

View raw extracted JSON

{
  "study_type": "animal",
  "exposure": {
    "band": "ELF",
    "source": "therapeutic pulsed electromagnetic fields",
    "frequency_mhz": 0.05,
    "sar_wkg": null,
    "duration": "1 hour/day for 4 months"
  },
  "population": "Female rats aged ten months with post-menopausal osteoporosis induced by ovariectomy",
  "sample_size": null,
  "outcomes": [
    "Bone mass loss (bone mass)"
  ],
  "main_findings": "In ovariectomized female rats treated 1 hour/day for 4 months with 50 Hz pulsed magnetic fields, 30 Gauss maximum intensity slowed bone mass loss to within about 10%. With 70 Gauss maximum intensity, no significant bone mass loss was observed.",
  "effect_direction": "benefit",
  "limitations": [
    "Preliminary results",
    "Sample size not reported in abstract",
    "Details of study design and outcome measurement methods not reported in abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "pulsed electromagnetic fields",
    "pulsed magnetic fields",
    "50 Hz",
    "30 Gauss",
    "70 Gauss",
    "osteoporosis",
    "ovariectomy",
    "rat",
    "bone mass"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: Not supplied
PubMed: 8155304

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