Effects of acute electromagnetic fields exposure on the interhemispheric homotopic functional connectivity during resting state.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2015 · Mixed · Low evidence

← Research stream

MixedLow evidencePaper 4718

In 30-minute real vs sham LTE-related RF exposure at 2.573 GHz (within safety limits), resting-state fMRI analyses suggested modulation of interhemispheric homotopic functional connectivity, particularly around the medial frontal gyrus and the paracentral lob…

Study snapshot

PublicationAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2015

Study typerandomized_trial

Reported directionMixed

Evidence ratingLow

Abstract

In this paper, we aimed to investigate the possible effects of acute radiofrequency electromagnetic fields (EMF) on the interhemispheric homotopic functional connectivity with resting state functional magnetic resonance imaging (fMRI) technique. We designed a controllable LTE-related EMF exposure environment at 2.573 GHz and performed the 30 min real/sham exposure experiments on human brain under the safety limits. The resting state fMRI signals were collected before and after EMF exposure. Then voxel-mirrored homotopic connectivity method was utilized to evaluate the acute effects of LTE EMF exposure on the homotopic functional connectivity between two human hemispheres. Based on our previous research, we further demonstrated that the 30 min short-term LTE EMF exposure would modulate the interhemispheric homotopic functional connectivity in resting state around the medial frontal gyrus and the paracentral lobule during the real exposure.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typerandomized_trial

Effect directionmixed

PopulationHumans (resting-state fMRI participants)

Sample sizeNot supplied

ExposureRF · 2573 MHz · 30 min (real/sham)

Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

Outcomes measured

Interhemispheric homotopic functional connectivity (voxel-mirrored homotopic connectivity) during resting state fMRI
Resting-state fMRI signals pre- vs post-exposure

Limitations

Sample size not reported in abstract
Exposure metric details (e.g., SAR, field strength) not reported in abstract
Only acute (30 min) exposure assessed
Clinical or behavioral significance of connectivity modulation not reported

View raw extracted JSON

{
  "study_type": "randomized_trial",
  "exposure": {
    "band": "RF",
    "source": "LTE-related EMF exposure environment",
    "frequency_mhz": 2573,
    "sar_wkg": null,
    "duration": "30 min (real/sham)"
  },
  "population": "Humans (resting-state fMRI participants)",
  "sample_size": null,
  "outcomes": [
    "Interhemispheric homotopic functional connectivity (voxel-mirrored homotopic connectivity) during resting state fMRI",
    "Resting-state fMRI signals pre- vs post-exposure"
  ],
  "main_findings": "In 30-minute real vs sham LTE-related RF exposure at 2.573 GHz (within safety limits), resting-state fMRI analyses suggested modulation of interhemispheric homotopic functional connectivity, particularly around the medial frontal gyrus and the paracentral lobule during real exposure.",
  "effect_direction": "mixed",
  "limitations": [
    "Sample size not reported in abstract",
    "Exposure metric details (e.g., SAR, field strength) not reported in abstract",
    "Only acute (30 min) exposure assessed",
    "Clinical or behavioral significance of connectivity modulation not reported"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "radiofrequency",
    "LTE",
    "2.573 GHz",
    "acute exposure",
    "resting-state fMRI",
    "voxel-mirrored homotopic connectivity",
    "interhemispheric connectivity",
    "medial frontal gyrus",
    "paracentral lobule"
  ],
  "suggested_hubs": [
    {
      "slug": "who-icnirp",
      "weight": 0.25,
      "reason": "Mentions exposure conducted under safety limits; relevant to guideline context but no direct policy evaluation."
    }
  ]
}

AI can be wrong. Always verify against the paper.

AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1109/embc.2015.7318732
PubMed: 26736632

Read the original paper →

Related papers

← Back to the Research Library