[Mechanism of anesthetic action of magnetic fields].

Radiatsionnaia biologiia, radioecologiia · 1998 · Harm · Low evidence

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HarmLow evidencePaper 4093

After 30 minutes of in vivo exposure of white male rats to a constant static magnetic field (SMF) of 0.2 T, dehydration was detected in brain, kidney, and liver tissues. Ouabain binding at 5×10^-9 M decreased in brain, heart, spleen, and liver tissues and inc…

Study snapshot

PublicationRadiatsionnaia biologiia, radioecologiia · 1998
Study typeanimal
Reported directionHarm
Evidence ratingLow

Abstract

The dehydration effect is suggested as a mechanism of anesthetic action of magnetic fields. After half an hour of in vivo exposure in constant magnetic field of white male rats to SMF 0.2 T the dehydration of brain, kidney and liver tissues were detected, the decrease of ouabain binding in 5.10(-9) M concentration was detected in brain, heart, spleen and liver tissues and it was increased in kidney tissue. With prolongation of the exposure time the dehydration of the whole organism was observed.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionharm
PopulationWhite male rats (in vivo)
Sample sizeNot supplied
Exposure30 minutes (with mention of prolonged exposure time)
Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

After 30 minutes of in vivo exposure of white male rats to a constant static magnetic field (SMF) of 0.2 T, dehydration was detected in brain, kidney, and liver tissues. Ouabain binding at 5×10^-9 M decreased in brain, heart, spleen, and liver tissues and increased in kidney tissue; with longer exposure, dehydration of the whole organism was observed.

Outcomes measured

  • Tissue dehydration (brain, kidney, liver)
  • Ouabain binding changes in tissues (brain, heart, spleen, liver, kidney)
  • Whole-organism dehydration with prolonged exposure

Limitations

  • Sample size not reported in abstract
  • Comparative design details and control conditions not described in abstract
  • Exposure duration beyond 30 minutes not quantified in abstract
  • Mechanistic interpretation (dehydration as anesthetic mechanism) is suggested rather than demonstrated in abstract
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": null,
    "source": "static magnetic field (SMF)",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": "30 minutes (with mention of prolonged exposure time)"
  },
  "population": "White male rats (in vivo)",
  "sample_size": null,
  "outcomes": [
    "Tissue dehydration (brain, kidney, liver)",
    "Ouabain binding changes in tissues (brain, heart, spleen, liver, kidney)",
    "Whole-organism dehydration with prolonged exposure"
  ],
  "main_findings": "After 30 minutes of in vivo exposure of white male rats to a constant static magnetic field (SMF) of 0.2 T, dehydration was detected in brain, kidney, and liver tissues. Ouabain binding at 5×10^-9 M decreased in brain, heart, spleen, and liver tissues and increased in kidney tissue; with longer exposure, dehydration of the whole organism was observed.",
  "effect_direction": "harm",
  "limitations": [
    "Sample size not reported in abstract",
    "Comparative design details and control conditions not described in abstract",
    "Exposure duration beyond 30 minutes not quantified in abstract",
    "Mechanistic interpretation (dehydration as anesthetic mechanism) is suggested rather than demonstrated in abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "static magnetic field",
    "SMF",
    "0.2 T",
    "rats",
    "dehydration",
    "ouabain binding",
    "mechanism",
    "anesthetic action"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: Not supplied
PubMed: 9889785

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