Effects of extremely low frequency electromagnetic fields on testes in guinea pig.

Pakistan journal of biological sciences : PJBS · 2007 · Harm · Low evidence

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HarmLow evidencePaper 3375

In exposed groups (0.013 µT at 5 Hz or 0.207 µT at 50 Hz; 2 or 4 hours/day for 5 days), testosterone levels decreased compared with control groups, with a reported significant difference (p < 0.001). Testes tissues showed main tissue changes in some treatment…

Study snapshot

PublicationPakistan journal of biological sciences : PJBS · 2007
Study typeanimal
Reported directionHarm
Evidence ratingLow

Abstract

This study is carried out to measure the changes in testosterone hormone level and changes in testes tissue on 36 adult male Guinea pigs that divided to 6 groups. Group A as control group exposed to nil Electromagnetic Field (EMF) for two hours per day for 5 days duration, group B exposed to 0.013 microT in 5 Hz to the Same duration period, group C exposed to 0.207 microT in 50 Hz in similar conditions, group D exposed for 4 h day(-1) for 5 days in 0.013 microT, group E tested in 0.207 microT as group D, group F used as controlled group exposed for four hours per day in nil electromagnetic field. Guinea pig blood was tested after 5 days. Then data analyzed by t-test. The results indicated a significantly difference between control group and tested group of four and two hours, testosterone level decreased (p < 0.001), also testes tissues were sampled and observed main tissue changes in some treatments.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionharm
PopulationAdult male guinea pigs
Sample size36
ExposureELF · 2 or 4 hours/day for 5 days
Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

In exposed groups (0.013 µT at 5 Hz or 0.207 µT at 50 Hz; 2 or 4 hours/day for 5 days), testosterone levels decreased compared with control groups, with a reported significant difference (p < 0.001). Testes tissues showed main tissue changes in some treatments.

Outcomes measured

  • Testosterone hormone level
  • Testes tissue changes (histological/tissue observations)

Limitations

  • Short exposure duration (5 days)
  • Statistical analysis described only as t-test; details of comparisons and effect sizes not provided in abstract
  • Tissue changes described qualitatively ("some treatments") without specifics in abstract
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "ELF",
    "source": "other",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": "2 or 4 hours/day for 5 days"
  },
  "population": "Adult male guinea pigs",
  "sample_size": 36,
  "outcomes": [
    "Testosterone hormone level",
    "Testes tissue changes (histological/tissue observations)"
  ],
  "main_findings": "In exposed groups (0.013 µT at 5 Hz or 0.207 µT at 50 Hz; 2 or 4 hours/day for 5 days), testosterone levels decreased compared with control groups, with a reported significant difference (p < 0.001). Testes tissues showed main tissue changes in some treatments.",
  "effect_direction": "harm",
  "limitations": [
    "Short exposure duration (5 days)",
    "Statistical analysis described only as t-test; details of comparisons and effect sizes not provided in abstract",
    "Tissue changes described qualitatively (\"some treatments\") without specifics in abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "extremely low frequency",
    "ELF",
    "electromagnetic fields",
    "guinea pig",
    "testosterone",
    "testes",
    "5 Hz",
    "50 Hz",
    "microtesla"
  ],
  "suggested_hubs": [
    {
      "slug": "elf-emf",
      "weight": 0.9,
      "reason": "Animal study of extremely low frequency EMF (5 Hz, 50 Hz) exposure and reproductive outcomes."
    }
  ]
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.3923/pjbs.2007.4519.4522
PubMed: 19093523

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