Radiofrequency waves with filling and peeling substances: An innovative minimally invasive technique for facial rejuvenation.

Dermatology and therapy · 2011 · Benefit · Low evidence

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BenefitLow evidencePaper 3192

In 112 treated patients, GAIS scores across five groups showed statistically significant improvement between 3 and 9 months after treatment. The authors conclude the SMP treatment was safe and effective for wrinkles, acne lesions, striae, and aging-related de…

Study snapshot

PublicationDermatology and therapy · 2011

Study typeother

Reported directionBenefit

Evidence ratingLow

Abstract

INTRODUCTION: This study describes a pivotal clinical trial of a new minimally invasive cosmetic procedure for facial rejuvenation and for the treatment of scars and wrinkles. METHODS: The procedure consisted of a combination of techniques such as fillers, biorevitalization, peeling, and intradermal radiofrequency, emitted from a new device denominated by Spherofill Medical Plus (SMP; Spherofill MD, PromoItalia Group S.p.A., Pozzuoli, Italy), for treating cutaneous regeneration, depressions, and striae. One hundred and twelve patients, divided into five groups, were treated. RESULTS: The results produced were statistically analyzed and resulted in significant and long-lasting effects for facial rejuvenation. Indeed, the analysis of the Global Aesthetic Improvement Scale (GAIS) scores in the five groups demonstrated statistically significant results between 3 and 9 months after the treatments. CONCLUSION: Evaluating the patients included in the study, it is possible to conclude that the treatment with SMP represents a safe and efficient solution for the treatment of wrinkles, acne lesions, striae, and of degenerated tissues caused by aging.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeother

Effect directionbenefit

PopulationPatients receiving minimally invasive cosmetic procedure for facial rejuvenation and treatment of scars/wrinkles (five groups)

Sample size112

ExposureRF

Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

Outcomes measured

Facial rejuvenation effectiveness
Global Aesthetic Improvement Scale (GAIS) scores
Wrinkles
Acne lesions
Striae
Safety

Limitations

No radiofrequency exposure parameters (e.g., frequency, power, SAR) reported in abstract
Study design details (e.g., randomization, control group, blinding) not described in abstract
Outcome measures beyond GAIS and safety not detailed in abstract

View raw extracted JSON

{
  "study_type": "other",
  "exposure": {
    "band": "RF",
    "source": "medical/cosmetic device (intradermal radiofrequency; Spherofill Medical Plus)",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Patients receiving minimally invasive cosmetic procedure for facial rejuvenation and treatment of scars/wrinkles (five groups)",
  "sample_size": 112,
  "outcomes": [
    "Facial rejuvenation effectiveness",
    "Global Aesthetic Improvement Scale (GAIS) scores",
    "Wrinkles",
    "Acne lesions",
    "Striae",
    "Safety"
  ],
  "main_findings": "In 112 treated patients, GAIS scores across five groups showed statistically significant improvement between 3 and 9 months after treatment. The authors conclude the SMP treatment was safe and effective for wrinkles, acne lesions, striae, and aging-related degenerated tissues.",
  "effect_direction": "benefit",
  "limitations": [
    "No radiofrequency exposure parameters (e.g., frequency, power, SAR) reported in abstract",
    "Study design details (e.g., randomization, control group, blinding) not described in abstract",
    "Outcome measures beyond GAIS and safety not detailed in abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "radiofrequency",
    "intradermal radiofrequency",
    "facial rejuvenation",
    "cosmetic procedure",
    "fillers",
    "peeling",
    "biorevitalization",
    "GAIS",
    "wrinkles",
    "scars",
    "striae",
    "acne"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1007/s13555-011-0001-3
PubMed: 22984657

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