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Liver lesion conspicuity during real-time MR-guided radiofrequency applicator placement using spoiled gradient echo and balanced steady-state free precession imaging.

Journal of magnetic resonance imaging : JMRI · 2014 · Unclear · Low evidence

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UnclearLow evidencePaper 3084

In 103 patients treated with MR-guided radiofrequency ablation, lesion detectability differed by sequence (spoiled GRE vs balanced SSFP) and lesion type. Overall, 20% of lesions could not be detected with either MR fluoroscopy sequence, implying 80% real-time…

Study snapshot

PublicationJournal of magnetic resonance imaging : JMRI · 2014
Study typeother
Reported directionUnclear
Evidence ratingLow

Abstract

PURPOSE: To retrospectively evaluate the conspicuity of liver lesions in a fluoroscopic spoiled gradient echo (GRE) and a balanced steady-state free precession (SSFP) magnetic resonance imaging (MRI) sequence. MATERIALS AND METHODS: In all, 103 patients with hepatocellular carcinomas (HCC) (41) or liver metastases (67) were treated using MR-guided radiofrequency ablation in a wide-bore 1.5 T scanner. A multislice real-time spoiled GRE sequence allowing for a T1 weighting (T1W) and a balanced SSFP sequence allowing for a T2/T1W contrast were used for MR guidance. The contrast-to-noise-ratio (CNR) of the lesions was calculated and lesion conspicuity was assessed retrospectively (easily detectable / difficult to detect / not detectable). RESULTS: HCC was easily detectable in 33/52% (GRE/SSFP), difficult to detect in 30/18%, and not detectable in 37/30% of the cases. Mean CNR varied widely (9.1 for GRE vs. 16.4 for SSFP). Liver metastases were easily detectable in 58/41% (GRE/SSFP), difficult to detect in 14/21%, and not detectable in 28/38% of the cases. Mean CNR for liver metastases was 11.5 (GRE) vs. 12.7 (SSFP). Twenty percent of all lesions could not be detected with either of the MR fluoroscopy sequences. CONCLUSION: MR fluoroscopy using GRE and SSFP contrast enabled real-time detectability of 80% of the liver lesions.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeother
Effect directionunclear
PopulationPatients with hepatocellular carcinoma (HCC) or liver metastases undergoing MR-guided radiofrequency ablation in a 1.5 T MRI scanner
Sample size103
ExposureNot supplied
Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

In 103 patients treated with MR-guided radiofrequency ablation, lesion detectability differed by sequence (spoiled GRE vs balanced SSFP) and lesion type. Overall, 20% of lesions could not be detected with either MR fluoroscopy sequence, implying 80% real-time detectability across sequences.

Outcomes measured

  • Liver lesion conspicuity (easily detectable / difficult to detect / not detectable)
  • Contrast-to-noise ratio (CNR)

Limitations

  • Retrospective evaluation
View raw extracted JSON
{
  "study_type": "other",
  "exposure": {
    "band": null,
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
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  },
  "population": "Patients with hepatocellular carcinoma (HCC) or liver metastases undergoing MR-guided radiofrequency ablation in a 1.5 T MRI scanner",
  "sample_size": 103,
  "outcomes": [
    "Liver lesion conspicuity (easily detectable / difficult to detect / not detectable)",
    "Contrast-to-noise ratio (CNR)"
  ],
  "main_findings": "In 103 patients treated with MR-guided radiofrequency ablation, lesion detectability differed by sequence (spoiled GRE vs balanced SSFP) and lesion type. Overall, 20% of lesions could not be detected with either MR fluoroscopy sequence, implying 80% real-time detectability across sequences.",
  "effect_direction": "unclear",
  "limitations": [
    "Retrospective evaluation"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "MRI",
    "MR fluoroscopy",
    "spoiled gradient echo",
    "balanced SSFP",
    "liver lesions",
    "hepatocellular carcinoma",
    "liver metastases",
    "MR-guided radiofrequency ablation",
    "contrast-to-noise ratio",
    "lesion conspicuity"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1002/jmri.24371
PubMed: 24677447

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