[The effect of weak low-frequency magnetic fields on the intracellular calcium-dependent proteinases of fish].

{
  "study_type": "animal",
  "exposure": {
    "band": "ELF",
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Crucian carp (Carassius carassius) and roach (Rutilus rutilus)",
  "sample_size": null,
  "outcomes": [
    "Activity of intracellular calcium-dependent proteinases (calpains) in skeletal muscles",
    "Activity of intracellular calcium-dependent proteinases (calpains) in brain"
  ],
  "main_findings": "In vivo and in vitro exposure to weak, low-frequency magnetic fields with resonance parameters for calcium ions was associated with a considerable decrease in calpain activity in fish skeletal muscles and brain.",
  "effect_direction": "mixed",
  "limitations": [
    "No exposure details provided (e.g., frequency, field strength, duration)",
    "Sample size not reported",
    "Quantitative results and statistical details not provided",
    "Unclear experimental design details for in vivo vs in vitro components"
  ],
  "evidence_strength": "low",
  "confidence": 0.66,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "low-frequency magnetic field",
    "ELF",
    "calcium ion resonance",
    "calpains",
    "fish",
    "crucian carp",
    "roach",
    "skeletal muscle",
    "brain",
    "in vivo",
    "in vitro"
  ],
  "suggested_hubs": [
    {
      "slug": "animal-studies",
      "weight": 0.9,
      "reason": "Study examines biological effects of low-frequency magnetic fields in fish (in vivo and in vitro)."
    }
  ]
}