RF Safe

Radiofrequency Electromagnetic Field Affects Heart Rate Variability in Rabbits

2020 · Mixed · Low evidence

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MixedLow evidencePaper 2125

In 21 rabbits, exposure to RF EMF (160 V/m for 150 min; either a device-generated 1788 MHz source or real base-station downlink 1805–1870 MHz under anesthesia) was associated with increased HRV parameters (HF-HRV, rMSSD) and lower heart rate, interpreted as i…

Study snapshot

Publicationmanual · 2020
Study typeanimal
Reported directionMixed
Evidence ratingLow

Abstract

Radiofrequency Electromagnetic Field Affects Heart Rate Variability in Rabbits Jakub Misek, Marcel Veternik, Ingrid Tonhajzerova, et al. Radiofrequency Electromagnetic Field Affects Heart Rate Variability in Rabbits. Physiological Research. 69(4):633-643. Aug 2020. Summary The aim of this study was to assess the effects of radiofrequency electromagnetic field (RF EMF) on heart rate variability (HRV) in rabbits with intensity slightly exceeding the limits for occupations. Totally 21 New Zealand white rabbits divided into two groups were used in this double-blind study. The first group of animals without general anesthesia was subjected to HRV examination under exposure to a device generated RF EMF source (frequency 1788 MHz, intensity 160 V/m, lasting 150 min.). The second group (premedications +α chloralose mg/kg) underwent the same protocol under the exposure to the real RF EMF signal from the base stations of mobile providers (frequency range 1805 - 1870 MHz -corresponding to the downlink signal of Slovak mobile providers, 160 V/m, 150 min., respectively). Individual 5-min records were used to analyze the HRV parameters: heart rate and root Mean Square of the Successive Differences (rMSSD) for time domain analysis and spectral powers in the low (LF-VFS) and high frequency (HF-VFS) bands for frequency domain analysis. Our study revealed the increased in HRV parameters (HF-HRV, rMSSD) associated with lower heart rate indicating increased cardiac vagal control under the exposure to RF EMF in experimental methods. Open access paper: biomed.cas.cz

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionmixed
PopulationNew Zealand white rabbits
Sample size21
ExposureRF · 1788 MHz · 150 min
Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

In 21 rabbits, exposure to RF EMF (160 V/m for 150 min; either a device-generated 1788 MHz source or real base-station downlink 1805–1870 MHz under anesthesia) was associated with increased HRV parameters (HF-HRV, rMSSD) and lower heart rate, interpreted as increased cardiac vagal control during exposure.

Outcomes measured

  • heart rate variability (HRV)
  • heart rate
  • rMSSD
  • HF-HRV (high-frequency spectral power)
  • LF-VFS (low-frequency spectral power)
  • HF-VFS (high-frequency spectral power)

Limitations

  • No sham/control (unexposed) condition described in the abstract
  • Two exposure conditions differ beyond RF source (anesthesia/premedication present in one group)
  • Intensity reported as V/m; SAR not reported
  • Short-term exposure only (150 min)
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": "base station",
    "frequency_mhz": 1788,
    "sar_wkg": null,
    "duration": "150 min"
  },
  "population": "New Zealand white rabbits",
  "sample_size": 21,
  "outcomes": [
    "heart rate variability (HRV)",
    "heart rate",
    "rMSSD",
    "HF-HRV (high-frequency spectral power)",
    "LF-VFS (low-frequency spectral power)",
    "HF-VFS (high-frequency spectral power)"
  ],
  "main_findings": "In 21 rabbits, exposure to RF EMF (160 V/m for 150 min; either a device-generated 1788 MHz source or real base-station downlink 1805–1870 MHz under anesthesia) was associated with increased HRV parameters (HF-HRV, rMSSD) and lower heart rate, interpreted as increased cardiac vagal control during exposure.",
  "effect_direction": "mixed",
  "limitations": [
    "No sham/control (unexposed) condition described in the abstract",
    "Two exposure conditions differ beyond RF source (anesthesia/premedication present in one group)",
    "Intensity reported as V/m; SAR not reported",
    "Short-term exposure only (150 min)"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "radiofrequency",
    "RF EMF",
    "1788 MHz",
    "1805-1870 MHz",
    "base stations",
    "downlink",
    "heart rate variability",
    "HRV",
    "rMSSD",
    "HF-HRV",
    "rabbits",
    "animal study",
    "double-blind"
  ],
  "suggested_hubs": [
    {
      "slug": "occupational-exposure",
      "weight": 0.55,
      "reason": "Exposure intensity described as slightly exceeding occupational limits."
    }
  ]
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: Not supplied
PubMed: Not supplied

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