RF Safe

Radiofrequency electromagnetic field affects heart rate variability in rabbits

2020 · Mixed · Low evidence

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MixedLow evidencePaper 1475

In 21 rabbits exposed for 150 minutes to RF EMF at 160 V/m (1788 MHz device-generated source or 1805–1870 MHz base-station downlink signal), HRV parameters increased (HF-HRV, rMSSD) and heart rate decreased, interpreted as increased cardiac vagal control unde…

Study snapshot

Publicationmanual · 2020
Study typeanimal
Reported directionMixed
Evidence ratingLow

Abstract

Radiofrequency electromagnetic field affects heart rate variability in rabbits J Misek, M Veterník, I Tonhajzerova, V Jakusova, L Janousek, J Jakus. Radiofrequency electromagnetic field affects heart rate variability in rabbits. Physiol Res. 2020 Jul 16. Abstract The aim of this study was to assess the effects of radiofrequency electromagnetic field (RF EMF) on heart rate variability (HRV) in rabbits with intensity slightly exceeding the limits for occupations. Totally 21 New Zealand white rabbits divided into two groups were used in this double-blind study. The first group of animals without general anesthesia was subjected to HRV examination under exposure to a device generated RF EMF source (frequency 1788 MHz, intensity 160 V/m, lasting 150 min.). The second group (premedications + alpha chloralose mg/kg) underwent the same protocol under the exposure to the real RF EMF signal from the base stations of mobile providers (frequency range 1805 - 1870 MHz - corresponding to the downlink signal of Slovak mobile providers, 160 V/m, 150 min., respectively). Individual 5 min records were used to analyze the HRV parameters: heart rate and root Mean Square of the Successive Differences (rMSSD) for time domain analysis and spectral powers in the low (LF-VFS) and high frequency (HF-VFS) bands for frequency domain analysis. Our study revealed the increase in HRV parameters (HF-HRV, rMSSD) associated with lower heart rate indicating increased cardiac vagal control under the exposure to RF EMF in experimental methods. Open access paper: biomed.cas.cz

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal
Effect directionmixed
PopulationNew Zealand white rabbits
Sample size21
ExposureRF · 1788 MHz · 150 min
Evidence strengthLowConfidence: 74% · Peer reviewed: unknown

Main findings

In 21 rabbits exposed for 150 minutes to RF EMF at 160 V/m (1788 MHz device-generated source or 1805–1870 MHz base-station downlink signal), HRV parameters increased (HF-HRV, rMSSD) and heart rate decreased, interpreted as increased cardiac vagal control under RF EMF exposure.

Outcomes measured

  • heart rate variability (HRV)
  • heart rate
  • rMSSD
  • LF-VFS spectral power
  • HF-VFS spectral power

Limitations

  • No sham/control (unexposed) group described in the abstract
  • Two exposure conditions differ in anesthesia status (one without general anesthesia; the other with premedication + alpha chloralose), which may confound comparisons
  • No quantitative effect sizes or statistical significance reported in the abstract
  • Journal name not provided in metadata (though cited as Physiol Res in abstract)
View raw extracted JSON
{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": "base station",
    "frequency_mhz": 1788,
    "sar_wkg": null,
    "duration": "150 min"
  },
  "population": "New Zealand white rabbits",
  "sample_size": 21,
  "outcomes": [
    "heart rate variability (HRV)",
    "heart rate",
    "rMSSD",
    "LF-VFS spectral power",
    "HF-VFS spectral power"
  ],
  "main_findings": "In 21 rabbits exposed for 150 minutes to RF EMF at 160 V/m (1788 MHz device-generated source or 1805–1870 MHz base-station downlink signal), HRV parameters increased (HF-HRV, rMSSD) and heart rate decreased, interpreted as increased cardiac vagal control under RF EMF exposure.",
  "effect_direction": "mixed",
  "limitations": [
    "No sham/control (unexposed) group described in the abstract",
    "Two exposure conditions differ in anesthesia status (one without general anesthesia; the other with premedication + alpha chloralose), which may confound comparisons",
    "No quantitative effect sizes or statistical significance reported in the abstract",
    "Journal name not provided in metadata (though cited as Physiol Res in abstract)"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "unknown",
  "keywords": [
    "radiofrequency electromagnetic field",
    "RF EMF",
    "heart rate variability",
    "HRV",
    "rMSSD",
    "HF-HRV",
    "LF",
    "HF",
    "rabbits",
    "base stations",
    "occupational limits",
    "1788 MHz",
    "1805-1870 MHz",
    "160 V/m"
  ],
  "suggested_hubs": [
    {
      "slug": "occupational-exposure",
      "weight": 0.6,
      "reason": "Exposure intensity described as slightly exceeding limits for occupations."
    }
  ]
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: Not supplied
PubMed: Not supplied

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