Effect of RFEMR on NSE and MDA levels in Sprague Dawley rats

2022 · Harm · Low evidence

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HarmLow evidencePaper 1271

The study reports a significant increase in NSE and MDA levels in rats exposed to mobile phone RFEMR.

Study snapshot

Publicationmanual · 2022

Study typeanimal

Reported directionHarm

Evidence ratingLow

Abstract

Effect of RFEMR on NSE and MDA levels in Sprague Dawley rats Pagadala, P; Shankar, V and Sumathi, ME. Effect of RFEMR on NSE and MDA levels in Sprague Dawley rats. Jun 2022. Bioinformation.18 (6): 501-505. Abstract Radiofrequency emitted radiations (RFEMR) from mobile phones are known to produce a stress response because of its effect on hypothalamus. Mobile phones have become an integral part of our lives with increasing usage not only in terms of number of users but also increase in talk time. Therefore, it is of interest to study the effect of mobile phone radiofrequency electromagnetic radiations on NSE and MDA levels in SD rats. Twelve male SD rats of 10-12weeks old, weighing 180-220 grams, were purchased from registered laboratory breeders & housed in a room with 12:12hour's light-dark cycle with adlibitum amount of food and RO water. Present study showed significant increase in NSE and MDA levels in rats exposed to RFEMR. This study proves that mobile RFEMR causes oxidative stress and oxidative damage in SD rats. bioinformation.net

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeanimal

Effect directionharm

PopulationMale Sprague Dawley rats (10–12 weeks old; 180–220 g)

Sample size12

ExposureRF

Evidence strengthLowConfidence: 72% · Peer reviewed: yes

Main findings

The study reports a significant increase in NSE and MDA levels in rats exposed to mobile phone RFEMR.

Outcomes measured

NSE levels
MDA levels
Oxidative stress/oxidative damage (as interpreted by authors)

Limitations

Exposure parameters (e.g., frequency, SAR, duration) not reported in the abstract
No details provided on control/sham conditions in the abstract
Small sample size

View raw extracted JSON

{
  "study_type": "animal",
  "exposure": {
    "band": "RF",
    "source": "mobile phone",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Male Sprague Dawley rats (10–12 weeks old; 180–220 g)",
  "sample_size": 12,
  "outcomes": [
    "NSE levels",
    "MDA levels",
    "Oxidative stress/oxidative damage (as interpreted by authors)"
  ],
  "main_findings": "The study reports a significant increase in NSE and MDA levels in rats exposed to mobile phone RFEMR.",
  "effect_direction": "harm",
  "limitations": [
    "Exposure parameters (e.g., frequency, SAR, duration) not reported in the abstract",
    "No details provided on control/sham conditions in the abstract",
    "Small sample size"
  ],
  "evidence_strength": "low",
  "confidence": 0.72,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "RFEMR",
    "radiofrequency",
    "mobile phone",
    "Sprague Dawley rats",
    "NSE",
    "MDA",
    "oxidative stress"
  ],
  "suggested_hubs": [
    {
      "slug": "mobile-phones",
      "weight": 0.9,
      "reason": "Exposure described as radiofrequency electromagnetic radiation from mobile phones."
    }
  ]
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: Not supplied
PubMed: Not supplied

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