Smart devices/mobile phone in patients with epilepsy? A systematic review
← Research streamThis systematic review identified 33 relevant studies (19 animal/computational and 14 human). Findings were mixed: about half of animal studies and half of human studies suggested detrimental effects of EMFs on brain function/seizure activity, while the remai…
Study snapshot
Abstract
Smart devices/mobile phone in patients with epilepsy? A systematic review Ali A Asadi-Pooya, Nafiseh Mirzaei Damabi, Marzieh Rostaminejad, Mina Shahisavandi, Anahita Asadi-Pooya. Smart devices/mobile phone in patients with epilepsy? A systematic review. Acta Neurol Scand. 2021 Jun 28. doi: 10.1111/ane.13492. Abstract We systematically reviewed the existing literature on the safety of the use of smartphone, mobile phone/Internet, and Wi-Fi by people with epilepsy (PWE), according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Scopus, MEDLINE, and Google Scholar from the inception to April 9, 2021 were searched. These key words were used "epilepsy" OR "seizure" AND "Mobile Phone" OR "Cell Phone" OR "Smartphone" OR "Wi-Fi" OR "Electromagnetic" OR "Radiation." The primary search yielded 7766 studies; 33 studies were related. In total, 19 manuscripts were based on animal/computational studies and 14 articles reported human investigations. Among animal studies, 10 articles suggested detrimental effects by electromagnetic fields (EMFs) on brain function/seizure activity, while nine studies negated this hypothesis. Among human studies, seven studies suggested detrimental effects by EMFs on brain function/seizure activity, while seven studies negated this hypothesis. None of the studies provided a good level of evidence. In one human study, all seven patients with epilepsy and abnormal EEG during the sham exposure, had an increase in the number of epileptic events with exposure to mobile phone radiation. In another study of the detrimental effects of smart technology device overuse among school students, an association was found between reporting seizures and the hours of smart technology device use. While high- quality evidence on the safety of the use of smartphone, mobile phone/Internet, and Wi-Fi in PWE is lacking, prudent use of these technologies, including using wired hand-free sets or other exposure-reducing measures is recommended. pubmed.ncbi.nlm.nih.gov
AI evidence extraction
Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.
Main findings
This systematic review identified 33 relevant studies (19 animal/computational and 14 human). Findings were mixed: about half of animal studies and half of human studies suggested detrimental effects of EMFs on brain function/seizure activity, while the remainder did not. The authors state that none of the included studies provided a good level of evidence and recommend prudent, exposure-reducing use.
Outcomes measured
- Brain function
- Seizure activity
- EEG abnormalities
- Reported seizures (association with device use hours)
Limitations
- None of the included studies provided a good level of evidence (as stated by the authors).
- Heterogeneity across included studies (animal/computational vs human; different technologies/exposures) implied by the review summary.
- Specific exposure metrics (e.g., frequency, SAR, duration) are not summarized in the abstract.
View raw extracted JSON
{
"publication_year": null,
"study_type": "systematic_review",
"exposure": {
"band": "RF",
"source": "mobile phone",
"frequency_mhz": null,
"sar_wkg": null,
"duration": null
},
"population": "People with epilepsy (PWE); also mentions school students in one included study",
"sample_size": null,
"outcomes": [
"Brain function",
"Seizure activity",
"EEG abnormalities",
"Reported seizures (association with device use hours)"
],
"main_findings": "This systematic review identified 33 relevant studies (19 animal/computational and 14 human). Findings were mixed: about half of animal studies and half of human studies suggested detrimental effects of EMFs on brain function/seizure activity, while the remainder did not. The authors state that none of the included studies provided a good level of evidence and recommend prudent, exposure-reducing use.",
"effect_direction": "mixed",
"limitations": [
"None of the included studies provided a good level of evidence (as stated by the authors).",
"Heterogeneity across included studies (animal/computational vs human; different technologies/exposures) implied by the review summary.",
"Specific exposure metrics (e.g., frequency, SAR, duration) are not summarized in the abstract."
],
"evidence_strength": "high",
"confidence": 0.74,
"peer_reviewed_likely": "yes",
"stance": "concern",
"stance_confidence": 0.62,
"summary": "This PRISMA-guided systematic review assessed literature on the safety of smartphones/mobile phone/Internet and Wi-Fi use in people with epilepsy. Across 33 included studies, results were mixed in both animal/computational and human investigations, with roughly equal numbers reporting detrimental versus no detrimental effects on brain function or seizure activity. The authors conclude that high-quality evidence is lacking and recommend prudent, exposure-reducing practices.",
"key_points": [
"The search (to April 9, 2021) yielded 33 studies related to epilepsy/seizures and mobile phone/smartphone/Wi-Fi/EMF exposure.",
"Included evidence comprised 19 animal/computational studies and 14 human studies.",
"Animal/computational findings were split: 10 studies suggested detrimental effects on brain function/seizure activity and nine did not.",
"Human findings were also split: seven studies suggested detrimental effects and seven did not.",
"The review states that none of the included studies provided a good level of evidence.",
"One included human study reported increased epileptic events during mobile phone radiation exposure among seven patients who had abnormal EEG during sham exposure.",
"Another included study reported an association between reporting seizures and hours of smart technology device use among school students.",
"The authors recommend prudent use and exposure-reducing measures (e.g., wired hands-free sets) due to limited high-quality evidence."
],
"categories": [
"Systematic Reviews",
"Mobile Phones",
"Wi-Fi",
"Neurology"
],
"tags": [
"Systematic Review",
"Epilepsy",
"Seizures",
"EEG",
"Mobile Phones",
"Smartphones",
"Wi-Fi",
"Radiofrequency Exposure",
"Electromagnetic Fields",
"Exposure Reduction"
],
"keywords": [
"epilepsy",
"seizure",
"mobile phone",
"cell phone",
"smartphone",
"Wi-Fi",
"electromagnetic",
"radiation",
"EEG",
"brain function"
],
"suggested_hubs": [
{
"slug": "cell-phones",
"weight": 0.9,
"reason": "Review focuses on mobile phone/smartphone radiation exposure and seizure-related outcomes."
},
{
"slug": "wifi",
"weight": 0.75,
"reason": "Wi-Fi exposure is explicitly included in the review scope and search terms."
}
],
"social": {
"tweet": "Systematic review (33 studies) on smartphone/mobile phone/Internet & Wi‑Fi use in people with epilepsy found mixed results (roughly half suggesting detrimental effects, half not) and concluded evidence quality is low; authors recommend prudent, exposure‑reducing use.",
"facebook": "A PRISMA-based systematic review of 33 studies examined whether smartphones/mobile phones/Internet and Wi‑Fi affect brain function or seizure activity in people with epilepsy. Results were mixed across animal/computational and human studies, and the authors noted that none provided a good level of evidence, recommending prudent, exposure‑reducing practices.",
"linkedin": "PRISMA-guided systematic review (33 studies) on smartphone/mobile phone/Internet and Wi‑Fi use in people with epilepsy reports mixed findings on brain function/seizure activity and emphasizes that evidence quality is poor; authors advise prudent, exposure‑reducing use."
}
}AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.
Identifiers and source
DOI: 10.1111/ane.13492
PubMed: 34180044
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