Parameter variation effects on millimeter wave dosimetry based on precise skin thickness in real rats

2023 · Unclear · Low evidence

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UnclearLow evidencePaper 383

Study snapshot

Publicationmanual · 2023

Study typeexposure_assessment

Reported directionUnclear

Evidence ratingLow

Abstract

Parameter variation effects on millimeter wave dosimetry based on precise skin thickness in real rats Li K, Hikage T, Masuda H, Ijima E, Nagai A, Taguchi K. Parameter variation effects on millimeter wave dosimetry based on precise skin thickness in real rats. Sci Rep. 2023 Oct 13;13(1):17397. doi: 10.1038/s41598-023-44572-y. Abstract This study presents a parametric analysis of the steady-state temperature elevation in rat skin models due to millimeter wave exposure at frequencies from 6-100 GHz. The statistical data of the thickness of skin layers, namely epidermis, dermis, dermal white adipose tissue, and panniculus carnosus, were measured for the first time using the excised tissues of real male Sprague-Dawley rats. Based on the precise structure obtained from the histological analysis of rat skin, we solve the bioheat transfer equation to investigate the effects of changes in parameters, such as body parts and thermal constants, on the absorbed power density and temperature elevation of biological tissues. Owing to the notably thin dermal white adipose tissue layer, the surface temperature elevation in the rat head and dorsal skin at 6-100 GHz is 52.6-32.3% and 83.3-58.8% of the average values of different human skin models, respectively. Our results also reveal that the surface temperature elevation of rat skin may correlate with the tissue thickness and deep blood perfusion rates. Open access paper: ncbi.nlm.nih.gov

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeexposure_assessment

Effect directionunclear

PopulationMale Sprague-Dawley rats (excised skin tissues used for measurements; rat skin models used for dosimetry/thermal calculations)

Sample sizeNot supplied

ExposuremmWave

Evidence strengthLowConfidence: 74% · Peer reviewed: yes

Main findings

Using histology-based rat skin layer thickness data and bioheat transfer modeling, the study reports that surface temperature elevation in rat head and dorsal skin at 6–100 GHz is 52.6–32.3% and 83.3–58.8%, respectively, of the average values from different human skin models. The results also indicate surface temperature elevation may correlate with tissue thickness and deep blood perfusion rates.

Outcomes measured

Absorbed power density (in modeled rat skin)
Steady-state temperature elevation / surface temperature elevation (modeled)
Measured thickness of rat skin layers (epidermis, dermis, dermal white adipose tissue, panniculus carnosus)

Limitations

Sample size not stated in the abstract
Modeling study (bioheat transfer equation) rather than in vivo exposure outcomes
Exposure conditions (e.g., incident power density) not specified in the abstract

View raw extracted JSON

{
  "study_type": "exposure_assessment",
  "exposure": {
    "band": "mmWave",
    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Male Sprague-Dawley rats (excised skin tissues used for measurements; rat skin models used for dosimetry/thermal calculations)",
  "sample_size": null,
  "outcomes": [
    "Absorbed power density (in modeled rat skin)",
    "Steady-state temperature elevation / surface temperature elevation (modeled)",
    "Measured thickness of rat skin layers (epidermis, dermis, dermal white adipose tissue, panniculus carnosus)"
  ],
  "main_findings": "Using histology-based rat skin layer thickness data and bioheat transfer modeling, the study reports that surface temperature elevation in rat head and dorsal skin at 6–100 GHz is 52.6–32.3% and 83.3–58.8%, respectively, of the average values from different human skin models. The results also indicate surface temperature elevation may correlate with tissue thickness and deep blood perfusion rates.",
  "effect_direction": "unclear",
  "limitations": [
    "Sample size not stated in the abstract",
    "Modeling study (bioheat transfer equation) rather than in vivo exposure outcomes",
    "Exposure conditions (e.g., incident power density) not specified in the abstract"
  ],
  "evidence_strength": "low",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "millimeter wave",
    "6-100 GHz",
    "dosimetry",
    "bioheat transfer equation",
    "temperature elevation",
    "rat skin model",
    "skin thickness",
    "histological analysis",
    "absorbed power density",
    "blood perfusion"
  ],
  "suggested_hubs": [
    {
      "slug": "5g-policy",
      "weight": 0.3,
      "reason": "Millimeter-wave frequencies (6–100 GHz) overlap with bands discussed in 5G/mmWave contexts, though this is a dosimetry/thermal modeling study rather than policy."
    }
  ]
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1038/s41598-023-44572-y
PubMed: Not supplied

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