RF Safe

Cellular and Molecular Effects of Magnetic Fields

International Journal of Molecular Sciences · 2024 · Mixed · Insufficient evidence

← Research stream
MixedInsufficient evidencePaper 59

This review summarizes in vitro and in vivo evidence that magnetic fields can influence cell behavior, including changes in gene expression, protein synthesis, and signaling pathways, and may interact with ion channels, membranes, and the cytoskeleton. It als…

Study snapshot

PublicationInternational Journal of Molecular Sciences · 2024
Study typereview
Reported directionMixed
Evidence ratingInsufficient

Abstract

Cellular and Molecular Effects of Magnetic Fields Tota M, Jonderko L, Witek J, Novickij V, Kulbacka J. Cellular and Molecular Effects of Magnetic Fields. Int J Mol Sci. 2024 Aug 17;25(16):8973. doi: 10.3390/ijms25168973. Abstract Recently, magnetic fields (MFs) have received major attention due to their potential therapeutic applications and biological effects. This review provides a comprehensive analysis of the cellular and molecular impacts of MFs, with a focus on both in vitro and in vivo studies. We investigate the mechanisms by which MFs influence cell behavior, including modifications in gene expression, protein synthesis, and cellular signaling pathways. The interaction of MFs with cellular components such as ion channels, membranes, and the cytoskeleton is analyzed, along with their effects on cellular processes like proliferation, differentiation, and apoptosis. Molecular insights are offered into how MFs modulate oxidative stress and inflammatory responses, which are pivotal in various pathological conditions. Furthermore, we explore the therapeutic potential of MFs in regenerative medicine, cancer treatment, and neurodegenerative diseases. By synthesizing current findings, this article aims to elucidate the complex bioeffects of MFs, thereby facilitating their optimized application in medical and biotechnological fields. Open access paper: mdpi.com

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typereview
Effect directionmixed
PopulationNot supplied
Sample sizeNot supplied
ExposureNot supplied
Evidence strengthInsufficientConfidence: 74% · Peer reviewed: yes

Main findings

This review summarizes in vitro and in vivo evidence that magnetic fields can influence cell behavior, including changes in gene expression, protein synthesis, and signaling pathways, and may interact with ion channels, membranes, and the cytoskeleton. It also describes reported effects on proliferation, differentiation, apoptosis, oxidative stress, and inflammatory responses, and discusses potential therapeutic applications in regenerative medicine, cancer, and neurodegenerative diseases.

Outcomes measured

  • gene expression
  • protein synthesis
  • cellular signaling pathways
  • ion channel interactions
  • membrane interactions
  • cytoskeleton interactions
  • cell proliferation
  • cell differentiation
  • apoptosis
  • oxidative stress
  • inflammatory responses
  • therapeutic applications (regenerative medicine, cancer treatment, neurodegenerative diseases)
View raw extracted JSON
{
  "study_type": "review",
  "exposure": {
    "band": null,
    "source": "other",
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": null,
  "sample_size": null,
  "outcomes": [
    "gene expression",
    "protein synthesis",
    "cellular signaling pathways",
    "ion channel interactions",
    "membrane interactions",
    "cytoskeleton interactions",
    "cell proliferation",
    "cell differentiation",
    "apoptosis",
    "oxidative stress",
    "inflammatory responses",
    "therapeutic applications (regenerative medicine, cancer treatment, neurodegenerative diseases)"
  ],
  "main_findings": "This review summarizes in vitro and in vivo evidence that magnetic fields can influence cell behavior, including changes in gene expression, protein synthesis, and signaling pathways, and may interact with ion channels, membranes, and the cytoskeleton. It also describes reported effects on proliferation, differentiation, apoptosis, oxidative stress, and inflammatory responses, and discusses potential therapeutic applications in regenerative medicine, cancer, and neurodegenerative diseases.",
  "effect_direction": "mixed",
  "limitations": [],
  "evidence_strength": "insufficient",
  "confidence": 0.74,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "magnetic fields",
    "cellular effects",
    "molecular effects",
    "in vitro",
    "in vivo",
    "gene expression",
    "protein synthesis",
    "signaling pathways",
    "ion channels",
    "membranes",
    "cytoskeleton",
    "proliferation",
    "differentiation",
    "apoptosis",
    "oxidative stress",
    "inflammation",
    "regenerative medicine",
    "cancer",
    "neurodegenerative diseases"
  ],
  "suggested_hubs": []
}
AI can be wrong. Always verify against the paper.

AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.3390/ijms25168973
PubMed: Not supplied

Read the original paper →

Related papers

← Back to the Research Library