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Provides an abstract excerpt from a mouse study of RF exposure and a saffron-derived compound, describing reproductive endpoints and reported changes in sperm and testicular tissue.
- Reproduction & pregnancy:
in the germinal epithelium and abnormal sperm were increased in Em group compared with the control group
- Research & federal duties:
y active component of saffron. So, this study was conducted to investigate the protective effect ofon the
- Proposed biological mechanisms:
rotein A2 (HspA2) immunoreactivity, and apoptosis were evaluated. Results: HspA2 immunoreactivity, apoptosis
http://www.ncbi.nlm.nih.gov/pubmed/32395207 Objectives: Exposure to electromagnetic fields (EMF) emitted from mobile phones may cause a deleterious effect on human health and may affect the male reproductive system., a carotenoid isolated from, is a phar¬macologically active component of saffron. So, this study was conducted to investigate the protective effect ofon the male reproductive system of 60 day old mice after EMF exposure.
Materials and Methods: Twenty-four male BALB/c mice were randomly divided into 4 groups: 1. Em group (2100 MHZ); 2. Cr group (50 mg/kg); 3. Em+Cr group (2100 MHZ+50 mg/kg), and 4. Control group. Sperm parameters (count, and abnormal percent), testis weight index, testis volume, seminiferous tubule diam¬eter, germinal epithelium thickness, LH, FSH and testosterone serum level, testicular Heat shock protein A2 (HspA2) immunoreactivity, and apoptosis were evaluated.
Results: HspA2 immunoreactivity, apoptosis in the germinal epithelium and abnormal sperm were increased in Em group compared with the control group