Measure of enzymatic activity coincident with 2450 MHz microwave exposure.

The Journal of microwave power · 1975 · No effect · Low evidence

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No effectLow evidencePaper 6122

Enzyme preparations exposed to 2450 MHz microwaves at an absorbed dose rate of 42 W/kg showed no difference in specific activity at 25°C compared with unirradiated controls.

Study snapshot

PublicationThe Journal of microwave power · 1975
Study typein_vitro
Reported directionNo effect
Evidence ratingLow

Abstract

Enzyme preparations were exposed to microwave radiation at 2450 MHz and enzymatic activity was simultaneously monitored spectrophotometrically with a crossed-beam exposure detection system. Enzymes studied were glucose 6-phosphate dehydrogenase from human red blood cells and yeast, adenylate kinase from rat liver mitochondria and rabbit muscle, and rat liver microsomal NADPH cytochrome c reductase. No difference was found between the specific activity at 25 degrees C of unirradiated controls and enzyme preparations irradiated at an absorbed dose rate of 42 W/kg.

Machine Enhanced Logic

AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typein_vitro
Effect directionno_effect
PopulationNot supplied
Sample sizeNot supplied
Exposuremicrowave · 2450 MHz · 42 W/kg
Evidence strengthLowConfidence: 78% · Peer reviewed: yes

Main findings

Enzyme preparations exposed to 2450 MHz microwaves at an absorbed dose rate of 42 W/kg showed no difference in specific activity at 25°C compared with unirradiated controls.

Outcomes measured

  • Enzymatic activity (specific activity) of glucose 6-phosphate dehydrogenase (human red blood cells and yeast)
  • Enzymatic activity (specific activity) of adenylate kinase (rat liver mitochondria and rabbit muscle)
  • Enzymatic activity (specific activity) of rat liver microsomal NADPH cytochrome c reductase

Limitations

  • Exposure duration not reported in abstract
  • Sample size/number of replicates not reported in abstract
  • Only one temperature condition (25°C) mentioned in abstract
  • In vitro enzyme preparations; findings may not generalize beyond the tested preparations and conditions
View raw extracted JSON
{
  "study_type": "in_vitro",
  "exposure": {
    "band": "microwave",
    "source": null,
    "frequency_mhz": 2450,
    "sar_wkg": 42,
    "duration": null
  },
  "population": null,
  "sample_size": null,
  "outcomes": [
    "Enzymatic activity (specific activity) of glucose 6-phosphate dehydrogenase (human red blood cells and yeast)",
    "Enzymatic activity (specific activity) of adenylate kinase (rat liver mitochondria and rabbit muscle)",
    "Enzymatic activity (specific activity) of rat liver microsomal NADPH cytochrome c reductase"
  ],
  "main_findings": "Enzyme preparations exposed to 2450 MHz microwaves at an absorbed dose rate of 42 W/kg showed no difference in specific activity at 25°C compared with unirradiated controls.",
  "effect_direction": "no_effect",
  "limitations": [
    "Exposure duration not reported in abstract",
    "Sample size/number of replicates not reported in abstract",
    "Only one temperature condition (25°C) mentioned in abstract",
    "In vitro enzyme preparations; findings may not generalize beyond the tested preparations and conditions"
  ],
  "evidence_strength": "low",
  "confidence": 0.78,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "2450 MHz",
    "microwave radiation",
    "enzyme activity",
    "spectrophotometry",
    "crossed-beam exposure detection system",
    "glucose 6-phosphate dehydrogenase",
    "adenylate kinase",
    "NADPH cytochrome c reductase",
    "absorbed dose rate",
    "42 W/kg"
  ],
  "suggested_hubs": []
}
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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1080/00222739.1975.11688968
PubMed: 175163

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