Exposure to a 50 Hz electromagnetic field induces activation of the Epstein-Barr virus genome in latently infected human lymphoid cells.

{
  "study_type": "in_vitro",
  "exposure": {
    "band": "ELF",
    "source": null,
    "frequency_mhz": 0.05,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Akata cells (human lymphoid cell line latently infected with Epstein–Barr virus genome)",
  "sample_size": null,
  "outcomes": [
    "Number of cells expressing Epstein–Barr virus (EBV) early antigens (activation of EBV genome)"
  ],
  "main_findings": "Exposure of Akata cells latently infected with EBV to a 50 Hz electromagnetic field increased the number of cells expressing EBV early antigens.",
  "effect_direction": "harm",
  "limitations": [
    "In vitro cell line study; findings may not generalize to humans or in vivo conditions",
    "Exposure parameters beyond frequency (e.g., field strength, duration) not provided in abstract",
    "Sample size and statistical details not reported in abstract"
  ],
  "evidence_strength": "very_low",
  "confidence": 0.72,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "50 Hz",
    "ELF electromagnetic field",
    "magnetic field",
    "Epstein-Barr virus",
    "EBV",
    "latent infection",
    "Akata cells",
    "early antigens",
    "viral activation",
    "lymphoid cells"
  ],
  "suggested_hubs": [
    {
      "slug": "elf-emf",
      "weight": 0.9,
      "reason": "Study examines biological effects of 50 Hz (ELF) electromagnetic field exposure."
    }
  ]
}