Magnetic field tomography of cortical and deep processes: examples of "real-time mapping" of averaged and single trial MEG signals.

International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 1995 · Unclear · Insufficient evidence

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UnclearInsufficient evidencePaper 4299

Study snapshot

PublicationInternational journal of psychophysiology : official journal of the International Organization of Psychophysiology · 1995

Study typeother

Reported directionUnclear

Evidence ratingInsufficient

Abstract

Magnetic field tomography (MFT) provides 3-dimensional estimates of brain activity, from non-contact, non-invasive measurements of the magnetic field generated by coherent electrical activity in the brain. MFT analysis of averaged auditory "odd-ball" data show cortical and deep activation, presumably from the amygdala and hippocampus. These results are compared with MFT estimates obtained from a patient who had undergone lobectomy which removed these structures. The variability from subject to subject is confounded by variability between trials for the same subject; the relationship between the averaged and single trials is probed by bi-hemispheric simultaneous measurements performed under the same odd-ball paradigm and by MFT analysis of auditory evoked data and interictal epileptic activity.

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AI evidence extraction

Structured fields below were generated from the paper’s abstract and metadata to make the evidence easier to inspect. Automated extraction may be incomplete or incorrect; verify important details against the original paper.

Study typeother

Effect directionunclear

PopulationPatient who had undergone lobectomy (auditory odd-ball paradigm); other subjects not further described

Sample sizeNot supplied

ExposureNot supplied

Evidence strengthInsufficientConfidence: 66% · Peer reviewed: yes

Main findings

MFT applied to averaged auditory odd-ball data showed cortical and deep activation, described as presumably from the amygdala and hippocampus, and these results were compared with MFT estimates from a lobectomy patient in whom these structures were removed. The abstract notes that subject-to-subject variability is confounded by trial-to-trial variability and describes probing the relationship between averaged and single-trial measurements using bi-hemispheric simultaneous recordings and MFT analysis of auditory evoked and interictal epileptic activity.

Outcomes measured

3-dimensional estimates of brain activity from MEG magnetic field measurements (Magnetic Field Tomography, MFT)
Cortical and deep activation during auditory odd-ball task (including presumed amygdala/hippocampus involvement)
Comparison of MFT estimates in lobectomy patient vs others
Trial-to-trial variability; relationship between averaged and single-trial signals
MFT analysis of auditory evoked data and interictal epileptic activity

Limitations

Sample size not reported in abstract
Population characteristics and inclusion criteria not described
Deep-source attribution described as 'presumably' (uncertain localization)
No quantitative results or statistical testing reported in abstract

View raw extracted JSON

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  "study_type": "other",
  "exposure": {
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    "source": null,
    "frequency_mhz": null,
    "sar_wkg": null,
    "duration": null
  },
  "population": "Patient who had undergone lobectomy (auditory odd-ball paradigm); other subjects not further described",
  "sample_size": null,
  "outcomes": [
    "3-dimensional estimates of brain activity from MEG magnetic field measurements (Magnetic Field Tomography, MFT)",
    "Cortical and deep activation during auditory odd-ball task (including presumed amygdala/hippocampus involvement)",
    "Comparison of MFT estimates in lobectomy patient vs others",
    "Trial-to-trial variability; relationship between averaged and single-trial signals",
    "MFT analysis of auditory evoked data and interictal epileptic activity"
  ],
  "main_findings": "MFT applied to averaged auditory odd-ball data showed cortical and deep activation, described as presumably from the amygdala and hippocampus, and these results were compared with MFT estimates from a lobectomy patient in whom these structures were removed. The abstract notes that subject-to-subject variability is confounded by trial-to-trial variability and describes probing the relationship between averaged and single-trial measurements using bi-hemispheric simultaneous recordings and MFT analysis of auditory evoked and interictal epileptic activity.",
  "effect_direction": "unclear",
  "limitations": [
    "Sample size not reported in abstract",
    "Population characteristics and inclusion criteria not described",
    "Deep-source attribution described as 'presumably' (uncertain localization)",
    "No quantitative results or statistical testing reported in abstract"
  ],
  "evidence_strength": "insufficient",
  "confidence": 0.66,
  "peer_reviewed_likely": "yes",
  "keywords": [
    "magnetic field tomography",
    "MEG",
    "auditory odd-ball",
    "amygdala",
    "hippocampus",
    "lobectomy",
    "single-trial analysis",
    "auditory evoked responses",
    "interictal epileptic activity"
  ],
  "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract and metadata and may be incomplete or incorrect. This material is for informational purposes and is not medical advice.

Identifiers and source

DOI: 10.1016/0167-8760(95)00031-3
PubMed: 8788219

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